Kaarela O I
Department of Surgery, Oulu University Central Hospital, Finland.
Scand J Plast Reconstr Surg Hand Surg. 1991;25(2):121-4. doi: 10.3109/02844319109111271.
Though vasospastic disorders of the hand are commonly treated by perivascular sympathectomy, which is believed to remove distal adrenergic innervation, our earlier experimental studies with rat saphenous vessels and rabbit ear vessels gave the opposite results. We therefore operated on 12 rabbits, carrying out perivascular sympathectomy of a metacarpal artery in the left forepaw, the right paw serving as a control. Six rabbits were killed after one week and the other six after three weeks, and the adrenergic nerves were examined by glyoxylic acid-induced fluorescence. Adrenergic innervation seemed to be normal in the distal vasculature after perivascular sympathectomy, and seemed to be missing only from the site of the operation.
尽管手部血管痉挛性疾病通常采用血管周围交感神经切除术进行治疗,人们认为该手术可去除远端肾上腺素能神经支配,但我们早期对大鼠隐静脉和兔耳血管进行的实验研究却得出了相反的结果。因此,我们对12只兔子进行了手术,在左前爪的一条掌动脉上实施血管周围交感神经切除术,右爪作为对照。6只兔子在一周后处死,另外6只在三周后处死,通过乙醛酸诱导荧光检查肾上腺素能神经。血管周围交感神经切除术后,远端血管系统中的肾上腺素能神经支配似乎正常,似乎仅在手术部位缺失。