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肥胖儿童身体适应性对胰岛素抵抗的影响。

The influence of fitness on insulin resistance in obese children.

机构信息

Department of Pediatrics, American Family Children's Hospital, University of Wisconsin, Madison, WI 53792, USA.

出版信息

Rev Endocr Metab Disord. 2009 Sep;10(3):189-96. doi: 10.1007/s11154-009-9109-5.

Abstract

An increasingly pervasive environment of reduced activity and easy access to high caloric food is leading to an epidemic of poor cardiovascular fitness, obesity, insulin resistance and type 2 diabetes (T2DM) in children. Studies have shown that insulin resistance (IR) to be an independent predictor for morbidity as well as mortality. These serve as a strong stimulus for public health strategies to improve fitness in children and adolescents. Methods to assess IR, improve IR and understand complications are increasingly important in children.

摘要

活动减少和高热量食物易获取的环境日益普遍,导致儿童心血管健康不良、肥胖、胰岛素抵抗和 2 型糖尿病(T2DM)流行。研究表明,胰岛素抵抗(IR)是发病率和死亡率的独立预测因素。这些为改善儿童和青少年健康的公共卫生策略提供了强有力的刺激。评估 IR、改善 IR 和了解并发症的方法在儿童中变得越来越重要。

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