Zia Sultani S, Nawaz Sarfraz A, Choudhary M Iqbal
H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi-75270, Pakistan.
Nat Prod Res. 2009;23(14):1265-73. doi: 10.1080/14786410500185303.
A new bisbenzylisoquinoline alkaloid, 1,2-dihydrokurramine (1), and four known bisbenzylisoquinoline alkaloids 2-5, along with a morphinan alkaloid 6 were isolated from Cocculus pendulus. The structures for these compounds were deduced by spectroscopic methods. All bisbenzylisoquinoline alkaloids showed inhibitory activities against acetyl- and butyrylcholinesterases.
从樟叶木防己中分离得到一种新的双苄基异喹啉生物碱1,2-二氢库拉明（1）、四种已知的双苄基异喹啉生物碱2 - 5以及一种吗啡烷生物碱6。通过光谱方法推导了这些化合物的结构。所有双苄基异喹啉生物碱均表现出对乙酰胆碱酯酶和丁酰胆碱酯酶的抑制活性。
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