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Studies on the mechanism of insulin action: basic concepts and clinical implications.

作者信息

Hepp K D

出版信息

Diabetologia. 1977 May;13(3):177-86. doi: 10.1007/BF01219697.

DOI:10.1007/BF01219697
PMID:194810
Abstract
摘要

相似文献

1
Studies on the mechanism of insulin action: basic concepts and clinical implications.胰岛素作用机制的研究:基本概念与临床意义。
Diabetologia. 1977 May;13(3):177-86. doi: 10.1007/BF01219697.
2
Antagonism of insulin and lipolytic hormones in the control of adenylate-cyclase activity in fat cells,
Eur J Biochem. 1974 Nov 1;49(1):129-41. doi: 10.1111/j.1432-1033.1974.tb03818.x.
3
Molecular events in the action of insulin on cell metabolism. The significance of cyclic AMP dependent protein kinases.胰岛素对细胞代谢作用中的分子事件。环磷酸腺苷依赖性蛋白激酶的意义。
Acta Endocrinol Suppl (Copenh). 1974;191:93-129. doi: 10.1530/acta.0.077s0093.
4
Effects of glucagon on cyclic AMP and carbohydrate metabolism in livers from diabetic rats.胰高血糖素对糖尿病大鼠肝脏中环磷酸腺苷及碳水化合物代谢的影响。
Biochim Biophys Acta. 1974 Mar 20;343(1):250-67. doi: 10.1016/0304-4165(74)90258-x.
5
Effects of dimethylsulfoxide on cyclic AMP accumulation, lipolysis and glucose metabolism of fat cells.二甲基亚砜对脂肪细胞中环磷酸腺苷积累、脂肪分解及葡萄糖代谢的影响。
Biochem Pharmacol. 1977 Apr 15;26(8):775-78. doi: 10.1016/0006-2952(77)90223-4.
6
Effects of lipolytic and antilipolytic agents on cyclic 3',5'-adenosine monophosphate in fat cells.脂解剂和抗脂解剂对脂肪细胞中环磷酸腺苷的影响。
J Biol Chem. 1971 Apr 10;246(7):2195-202.
7
Independence of the effects of epinephrine, glucagon, and adrenocorticotropin on glucose utilization from those on lipolysis in isolated rat adipose cells.肾上腺素、胰高血糖素和促肾上腺皮质激素对分离的大鼠脂肪细胞中葡萄糖利用的作用与对脂肪分解的作用相互独立。
J Biol Chem. 1969 Jul 10;244(13):3423-9.
8
Effects of thyroid hormone deficiency on cyclic adenosine 3':5'-monophosphate and control of lipolysis in fat cells.甲状腺激素缺乏对脂肪细胞中环磷酸腺苷及脂肪分解控制的影响。
J Biol Chem. 1974 Jul 10;249(13):4226-31.
9
Adenylate cyclase and insulin action. Effect of insulin, nonsuppressible insulin-like material, and diabetes on adenylate-cyclase activity in mouse liver.腺苷酸环化酶与胰岛素作用。胰岛素、不可抑制的胰岛素样物质及糖尿病对小鼠肝脏腺苷酸环化酶活性的影响。
Eur J Biochem. 1972 Dec 4;31(2):266-76. doi: 10.1111/j.1432-1033.1972.tb02529.x.
10
Effect of partially purified NSILA on adenylate cyclase, phosphodiesterase and 3',5'-cyclic AMP in fat cells.部分纯化的非抑制胰岛素样活性物质对脂肪细胞中腺苷酸环化酶、磷酸二酯酶及3',5'-环磷酸腺苷的作用
Mol Cell Endocrinol. 1975 Oct;3(4):309-21. doi: 10.1016/0303-7207(75)90012-x.

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1
Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes.肝脏乙酰辅酶A将脂肪组织炎症与肝脏胰岛素抵抗及2型糖尿病联系起来。
Cell. 2015 Feb 12;160(4):745-758. doi: 10.1016/j.cell.2015.01.012. Epub 2015 Feb 5.
2
Hepatic effects of glucose and insulin independent of cyclic nucleotide changes.葡萄糖和胰岛素的肝脏效应独立于环核苷酸变化。
Acta Diabetol Lat. 1981 Oct-Dec;18(4):297-310. doi: 10.1007/BF02042813.
3
A partial view of the mechanism of insulin action.胰岛素作用机制的部分观点。

本文引用的文献

1
The chemical combination of insulin with muscle (diaphragm) of normal rat.胰岛素与正常大鼠肌肉(膈肌)的化学结合。
Am J Med Sci. 1949 Sep;218(3):265-74. doi: 10.1097/00000441-194909000-00004.
2
Adenyl cyclase activity in a plasma membrane fraction purified from "ghosts" of rat fat cells.从大鼠脂肪细胞“血影”中纯化得到的质膜组分中的腺苷酸环化酶活性。
FEBS Lett. 1972 Mar;21(1):45-48. doi: 10.1016/0014-5793(72)80159-5.
3
Insulin action on the adenyl cyclase system: Antagonism to activation by lipolytic hormones.胰岛素对腺苷酸环化酶系统的作用:对脂解激素激活作用的拮抗。
Diabetologia. 1981 Oct;21(4):347-62. doi: 10.1007/BF00252681.
4
Insulin receptors and the clinician.胰岛素受体与临床医生。
Br Med J (Clin Res Ed). 1986 Apr 5;292(6525):919-22. doi: 10.1136/bmj.292.6525.919.
5
Relationship between body fat mass, carbohydrate tolerance and IRI response during glucose infusion in subjects with early diabetes.早期糖尿病患者葡萄糖输注期间体脂量、糖耐量与胰岛素抵抗指数反应之间的关系
Acta Diabetol Lat. 1979 Jan-Mar;16(1):67-75. doi: 10.1007/BF02590765.
6
Adenylate cyclase activity in the epididymal adipose tissue from obese-hyperglycaemic mice.肥胖高血糖小鼠附睾脂肪组织中的腺苷酸环化酶活性
Diabetologia. 1978 Jul;15(1):45-51. doi: 10.1007/BF01219328.
7
Effect of fasting and streptozotocin diabetes on insulin binding and action in the isolated mouse soleus muscle.禁食和链脲佐菌素诱导的糖尿病对分离的小鼠比目鱼肌中胰岛素结合及作用的影响。
J Clin Invest. 1979 Nov;64(5):1505-15. doi: 10.1172/JCI109609.
FEBS Lett. 1972 Feb 1;20(2):191-194. doi: 10.1016/0014-5793(72)80791-9.
4
Inhibition of glucagon-stimulated adenyl cyclase by insulin.胰岛素对胰高血糖素刺激的腺苷酸环化酶的抑制作用。
FEBS Lett. 1971 Jan 30;12(5):263-266. doi: 10.1016/0014-5793(71)80193-x.
5
Role of adenosine 3',5'-monophosphate in the effects of insulin and anti-insulin serum on liver metabolism.3',5'-环磷酸腺苷在胰岛素及抗胰岛素血清对肝脏代谢影响中的作用
J Biol Chem. 1968 Mar 10;243(5):1031-8.
6
Characterization of diabetes in the Chinese hamster.中国仓鼠糖尿病的特征描述。
Diabetologia. 1967 Apr;3(2):74-84. doi: 10.1007/BF01222182.
7
Interaction of insulin with the cell membrane: the primary action of insulin.胰岛素与细胞膜的相互作用:胰岛素的主要作用。
Proc Natl Acad Sci U S A. 1969 Jun;63(2):450-7. doi: 10.1073/pnas.63.2.450.
8
Insulin interactions with liver plasma membranes. Independence of binding of the hormone and its degradation.胰岛素与肝细胞膜的相互作用。激素结合与其降解的独立性。
J Biol Chem. 1972 Jun 25;247(12):3953-61.
9
Decreased insulin binding to lymphocytes from diabetic subjects.
J Clin Invest. 1974 Dec;54(6):1323-8. doi: 10.1172/JCI107878.
10
Effects of lipolytic and antilipolytic substances on adenosine 3',5'-monophosphate levels in isolated fat cells.脂解和抗脂解物质对分离脂肪细胞中3',5'-单磷酸腺苷水平的影响。
J Biol Chem. 1968 Apr 25;243(8):1705-12.