硫醇对淋巴细胞膜的作用。
The action of thiols on lymphocyte membranes.
作者信息
Ryzewski J, Roszkowski-Sliź W, Krzystyniak K
出版信息
Immunology. 1976 Jul;31(1):145-9.
Abstract
Short-term incubation with cysteine in concentrations not altering cell viability increased the amount of -SH groups on the surface of rat lymphocytes. Maximal effect was achieved in 10 min using 2 mM cysteine, which concentration also induced immediate total loss of response to adrenaline, as measured by intracellular cyclic AMP level. Neither of these effects was observed after incubation of lymphocytes with glutathione or dithiothreitol.
摘要
用浓度不改变细胞活力的半胱氨酸进行短期孵育，可增加大鼠淋巴细胞表面的-SH基团数量。使用2 mM半胱氨酸在10分钟内可达到最大效果，该浓度还会导致通过细胞内环磷酸腺苷水平测量的对肾上腺素的反应立即完全丧失。用谷胱甘肽或二硫苏糖醇孵育淋巴细胞后，未观察到这些效应。
相似文献
1
The action of thiols on lymphocyte membranes.硫醇对淋巴细胞膜的作用。
Immunology. 1976 Jul;31(1):145-9.
2
Studies on cyclic AMP-cyclic GMP cooperation and on the influence of acetylcholine, adrenaline and thiols in lymphocyte reactivity.关于环磷酸腺苷 - 环磷酸鸟苷协同作用以及乙酰胆碱、肾上腺素和硫醇对淋巴细胞反应性影响的研究。
Arch Immunol Ther Exp (Warsz). 1978;26(1-6):357-9.
3
4
Cysteine-induced changes of low molecular sulfhydryl/disulfide ratio in rat lymphoid cells.
Arch Immunol Ther Exp (Warsz). 1989;37(1-2):37-47.
5
The action of cysteine on PHA-stimulation of lymphocytes. I. Influence of DNA synthesis.半胱氨酸对淋巴细胞PHA刺激的作用。I. 对DNA合成的影响。
Arch Immunol Ther Exp (Warsz). 1977;25(3):377-83.
6
Studies on the influence of thiols on lymphocytes (T-type lymphocytes) function.硫醇对淋巴细胞（T 型淋巴细胞）功能影响的研究。
Arch Immunol Ther Exp (Warsz). 1978;26(1-6):361-5.
7
Interaction of 6,6'-dithiodinicotinic acid with rat thymocytes pretreated with thiol compounds.6,6'-二硫代烟酸与经硫醇化合物预处理的大鼠胸腺细胞的相互作用。
Arch Immunol Ther Exp (Warsz). 1976;24(1):109-14.
8
Alterations in cyclic AMP metabolism in human bronchial asthma. 3. Leukocyte and lymphocyte responses to steroids.人类支气管哮喘中环磷酸腺苷代谢的改变。3. 白细胞和淋巴细胞对类固醇的反应。
J Clin Invest. 1973 Jun;52(6):1342-8. doi: 10.1172/JCI107306.
9
[The use of liposomes for a study of cAMP transport by lymphocyte membranes].[脂质体用于淋巴细胞膜cAMP转运研究]
Biull Eksp Biol Med. 1990 Mar;109(3):246-8.
10
The influence of cysteine on adenyl cyclase activity in rat lymphocytes.半胱氨酸对大鼠淋巴细胞中腺苷酸环化酶活性的影响。
Arch Immunol Ther Exp (Warsz). 1974;22(5):619-23.
引用本文的文献
1
Gestational and Lactational Co-Exposure to DEHP and BPA Impairs Hepatic Function via PI3K/AKT/FOXO1 Pathway in Offspring.孕期和哺乳期同时暴露于邻苯二甲酸二（2-乙基己基）酯（DEHP）和双酚A（BPA）会通过PI3K/AKT/FOXO1信号通路损害子代肝脏功能。
Toxics. 2023 Feb 24;11(3):216. doi: 10.3390/toxics11030216.
2
Obesity, longevity, quality of life: alteration by dietary 2-mercaptoethanol.肥胖、长寿、生活质量：饮食 2-巯基乙醇的改变。
Virulence. 2010 Nov-Dec;1(6):509-15. doi: 10.4161/viru.1.6.13803. Epub 2010 Nov 1.
3
The immunopotentiating effect of thiosulphate in vivo.硫代硫酸盐在体内的免疫增强作用。
Experientia. 1977 Dec 15;33(12):1654-6. doi: 10.1007/BF01934054.
本文引用的文献
1
Repair of radiation damage to membrane sulfhydryl groups of human erythrocytes.
Biochim Biophys Acta. 1967 Jul 3;135(3):568-70. doi: 10.1016/0005-2736(67)90048-x.
2
Repair of radiation damage to erythrocyte membranes. The reduction of radiation-induced disulfide groups.红细胞膜辐射损伤的修复。辐射诱导二硫键的减少。
Radiat Res. 1968 May;34(2):300-14.
3
Modification of external sulfhydryl groups of Ehrlich ascites tumor cells with 6,6'-dithiodinicotinic acid.用6,6'-二硫代烟酸修饰艾氏腹水瘤细胞的外部巯基基团。
Biochem Pharmacol. 1970 May;19(5):1836-8. doi: 10.1016/0006-2952(70)90180-2.
4
The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. I. Properties.大鼠肝脏质膜中对胰高血糖素敏感的腺苷酸环化酶系统。I. 特性。
J Biol Chem. 1971 Mar 25;246(6):1849-56.
5
Sulfhydryl groups of the erythrocyte membrane and their relation to glycolysis and drug-induced hemolytic anemia.红细胞膜的巯基及其与糖酵解和药物诱导的溶血性贫血的关系。
J Clin Invest. 1974 Mar;53(3):805-12. doi: 10.1172/JCI107619.
6
Chemical modulation of cell surfaces by sulfhydryl compounds: effect on C3b receptors.巯基化合物对细胞表面的化学调节作用：对C3b受体的影响
J Immunol. 1974 Sep;113(3):940-7.
7
The influence of DL-cysteine on adenyl cyclase activity in rat thymocytes.DL-半胱氨酸对大鼠胸腺细胞中腺苷酸环化酶活性的影响。
Arch Immunol Ther Exp (Warsz). 1974;22(5):629-33.
8
Cyclic nucleotides as intracellular mediators of the expression of antigen-sensitive cells.环核苷酸作为抗原敏感细胞表达的细胞内介质。
Nature. 1973 Dec 14;246(5433):405-9. doi: 10.1038/246405a0.
9
Hormone-sensitive adenylyl cyclases. Useful models for studying hormone receptor functions in cell-free systems.激素敏感腺苷酸环化酶。用于在无细胞系统中研究激素受体功能的有用模型。
Biochim Biophys Acta. 1973 Sep 10;300(2):129-58. doi: 10.1016/0304-4157(73)90002-6.
10
The purification of bovine thyroid plasma membranes and the properties of membrane-bound adenyl cyclase.
J Biol Chem. 1971 Jun 25;246(12):3939-47.
Zotero 插件