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脑非典型畸胎样/横纹肌样瘤:病例系列及文献综述

Atypical teratoid rhabdoid tumor of the brain: case series and review of literature.

作者信息

Biswas Ahitagni, Goyal Shikha, Puri Tarun, Das Prasenjit, Sarkar Chitra, Julka Pramod Kumar, Bakhshi Sameer, Rath Goura Kishor

机构信息

Department of Radiotherapy and Oncology, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Childs Nerv Syst. 2009 Nov;25(11):1495-500. doi: 10.1007/s00381-009-0903-x. Epub 2009 May 30.

DOI:10.1007/s00381-009-0903-x
PMID:19484251
Abstract

INTRODUCTION

Intracranial atypical teratoid rhabdoid tumor is an uncommon malignancy with a dismal outcome. Commonly misdiagnosed over the decades as primitive neuroectodermal tumor of the brain, it has dramatically different biological behavior.

DISCUSSION

We herein report a case series of five patients diagnosed and treated as atypical teratoid rhabdoid tumor of the brain in a major cancer center in north India. We have also analyzed the clinical, histopathological, and radiological features and the therapeutic options of this enigmatic tumor.

摘要

引言

颅内非典型畸胎样横纹肌样瘤是一种罕见的恶性肿瘤,预后不佳。在过去几十年中,它常被误诊为脑原始神经外胚层肿瘤,但其生物学行为却截然不同。

讨论

我们在此报告在印度北部一家大型癌症中心诊断并治疗的5例脑非典型畸胎样横纹肌样瘤患者的病例系列。我们还分析了这种神秘肿瘤的临床、组织病理学和放射学特征以及治疗选择。

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