Han Jin H, Morandi Alessandro, Ely E Wesley, Callison Clay, Zhou Chuan, Storrow Alan B, Dittus Robert S, Habermann Ralf, Schnelle John
Department of Emergency Medicine, Vanderbilt University Medical Center, 703 Oxford House, Nashville, TN 37232-4700, USA.
J Am Geriatr Soc. 2009 May;57(5):889-94. doi: 10.1111/j.1532-5415.2009.02219.x.
To determine whether nursing home patients are more likely than non-nursing home patients to present to the emergency department (ED) with delirium and to explore how variations in their delirium risk factor profiles contribute to this relationship.
Prospective cross-sectional study.
Tertiary care academic ED.
Three hundred forty-one English-speaking patients aged 65 and older.
Delirium status was determined using the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) administered by trained research assistants. Multivariable logistic regression was used to determine whether nursing home residence was independently associated with delirium. Adjusted odds ratios (ORs) with their 95% confidence intervals (95% CIs) were reported.
Of the 341 patients enrolled, 58 (17.0%) resided in a nursing home and 38 (11.1%) were considered to have delirium in the ED. Of the 58, (22 (37.9%) nursing home patients and 16 of 283 (5.7%) non-nursing home patients had delirium; unadjusted OR=10.2, 95% CI=4.9-21.2). After adjusting for dementia, a Katz activity of daily living score less than or equal to 4, hearing impairment, and the presence of systemic inflammatory response syndrome, nursing home residence was independently associated with delirium in the ED (adjusted OR=4.2, 95% CI=1.8-9.7).
In the ED setting, nursing home patients were more likely to present with delirium, and this relationship persisted after adjusting for delirium risk factors.
确定疗养院患者与非疗养院患者相比,是否更有可能因谵妄而前往急诊科就诊,并探讨其谵妄风险因素概况的差异如何导致这种关系。
前瞻性横断面研究。
三级医疗学术急诊科。
341名65岁及以上讲英语的患者。
谵妄状态通过由训练有素的研究助理使用重症监护病房谵妄评估方法(CAM-ICU)来确定。多变量逻辑回归用于确定居住在疗养院是否与谵妄独立相关。报告了调整后的比值比(OR)及其95%置信区间(95%CI)。
在纳入的341名患者中,58名(17.0%)居住在疗养院,38名(11.1%)在急诊科被认为患有谵妄。在这58名患者中,22名(37.9%)疗养院患者和283名中的16名(5.7%)非疗养院患者患有谵妄;未调整的OR=10.2,95%CI=4.9-21.2。在调整痴呆、日常生活活动能力Katz评分小于或等于4、听力障碍和全身炎症反应综合征的存在后,居住在疗养院与急诊科谵妄独立相关(调整后的OR=4.2,95%CI=1.8-9.7)。
在急诊科环境中,疗养院患者更有可能出现谵妄,并且在调整谵妄风险因素后这种关系仍然存在。