意大利不同组织环境下肿瘤标志物的申请模式：医院实验室调查
Tumour markers requesting pattern with regards to different organizational settings in Italy: a survey of hospital laboratories.
作者信息
Franceschini Roberta, Trevisiol Chiara, Dittadi Ruggero, Gion Massimo
机构信息
Association ABO for the Application of Biotechnologies in Oncology c/o Centre for the Study of Biological Markers of Malignancy, Regional Hospital, AULSS 12, Venice, Italy,
出版信息
Ann Clin Biochem. 2009 Jul;46(Pt 4):316-21. doi: 10.1258/acb.2009.008240. Epub 2009 Jun 1.
BACKGROUND
Tumour markers are frequently used in clinical practice and the reason for ordering varies considerably and often seems to be inappropriate. We carried out a survey of Italian laboratories on their current pattern of use.
METHODS
Forty-four laboratories located in health-care institutions with inpatient beds were surveyed about the organizational, clinical and methodological aspects of tumour markers ordering.
RESULTS
Thirty-one laboratories (70%) filled in and returned the questionnaire. Overall, 977,786 tumour marker tests were scrutinized. The pattern of tumour marker use did not seem to be influenced by the institutional setting, by availability of oncology facilities or by adoption of clinical guidelines. In addition, the information flow from clinicians to the laboratory and vice versa was poor and informal.
CONCLUSIONS
Monitoring tumour marker pattern use can provide valuable information for health-care decision makers, highlighting potential inadequacies in laboratory services but also identifying problems in other areas of health-care delivery that could benefit from educational programmes.
背景
肿瘤标志物在临床实践中经常使用，其检测目的差异很大，且往往似乎并不恰当。我们对意大利的实验室进行了一项关于其当前使用模式的调查。
方法
对位于设有住院病床的医疗机构中的44家实验室进行了调查，内容涉及肿瘤标志物检测的组织、临床和方法学方面。
结果
31家实验室（70%）填写并返回了问卷。总共审查了977,786次肿瘤标志物检测。肿瘤标志物的使用模式似乎不受机构设置、肿瘤学设施的可用性或临床指南的采用情况的影响。此外，临床医生与实验室之间的信息流通不畅且不规范。
结论
监测肿瘤标志物的使用模式可为医疗保健决策者提供有价值的信息，突出实验室服务中潜在的不足之处，但也能识别医疗保健提供其他领域中可受益于教育计划的问题。
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