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[不同类型痛风性肾病的免疫学指标及肾脏结构受累程度]

[The immunological indices in different types of gouty nephropathy and the degree of renal structure involvement].

作者信息

Siniachenko O V, Nikolenko Iu I, Diadyk A I, Vasilenko I V, Kosheleva E N, Bortnik V A, Okushko R V

出版信息

Ter Arkh. 1991;63(6):37-41.

PMID:1948741
Abstract

Patients with different types of podagric nephropathy were examined for 21 indicators of the functional activity of T and B lymphocytes and neutrophils. The data obtained were compared to the degree of impairment of the basic renal structures. Among the study immunologic indicators to estimate the gravity of morphological alterations in the glomeruli, the decrease of the titers of antibodies to DNA is of definite specificity, whereas the fall of the concentration of circulating immune complexes is of definite specificity in the assessment of alteration in the stroma.

摘要

对不同类型痛风性肾病患者进行了T和B淋巴细胞以及中性粒细胞功能活性的21项指标检测。将所得数据与基本肾脏结构的损伤程度进行比较。在用于评估肾小球形态学改变严重程度的研究免疫指标中,抗DNA抗体滴度降低具有一定特异性,而循环免疫复合物浓度下降在评估基质改变方面具有一定特异性。

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