对IgA肾病患者肾小球沉积物中与IgA相关的免疫复合物的双重免疫荧光研究。
Double immunofluorescence studies on IgA-associated immune-complexes in glomerular deposits in patients with IgA nephropathy.
作者信息
Tomino Y, Nomoto Y, Endoh M, Sakai H, Arimori S
出版信息
Tokai J Exp Clin Med. 1980 Apr;5(2):147-9.
A study on double immunofluorescent staining of immunoglobulins and complement in IgA-associated immune-complexes of glomerular deposits in patients with IgA nephropathy is described. The components of immune-complexes deposited in kidney tissues included IgA, IgG, IgM, IgE, C3, C3A, properdin, Clq and C4. Although the majority of the deposits consisted of IgA and C3, some deposits showed the coexistence of other classes of immunoglobulins and C3 as well as other types of complement. It was suggested that the immune-complexes deposited in the glomeruli of patients with IgA nephropathy have a polyclonal nature.
本文描述了一项关于IgA肾病患者肾小球沉积物中IgA相关免疫复合物的免疫球蛋白和补体双重免疫荧光染色研究。沉积于肾组织中的免疫复合物成分包括IgA、IgG、IgM、IgE、C3、C3A、备解素、Clq和C4。尽管大多数沉积物由IgA和C3组成，但一些沉积物还显示出其他类免疫球蛋白与C3以及其他类型补体的共存。提示IgA肾病患者肾小球中沉积的免疫复合物具有多克隆性质。
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