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少数族裔队列中内脏脂肪组织量的五年变化:胰岛素抵抗动脉粥样硬化研究(IRAS)家族研究

Five-year change in visceral adipose tissue quantity in a minority cohort: the Insulin Resistance Atherosclerosis Study (IRAS) family study.

作者信息

Hairston Kristen G, Scherzinger Ann, Foy Capri, Hanley Anthony J, McCorkle Orita, Haffner Steven, Norris Jill M, Bryer-Ash Michael, Wagenknecht Lynne E

机构信息

Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.

出版信息

Diabetes Care. 2009 Aug;32(8):1553-5. doi: 10.2337/dc09-0336. Epub 2009 Jun 1.

DOI:10.2337/dc09-0336
PMID:19487643
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2713650/
Abstract

OBJECTIVE To describe the 5-year change in visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) areas. RESEARCH DESIGN AND METHODS Absolute change in VAT and SAT measured by abdominal computed tomography scans has been obtained at a 5-year interval from African Americans (n = 389) and Hispanic Americans (n = 844), aged 20-69 years, in 10-year age-groups. RESULTS Mean 5-year increases in VAT areas in women were 18, 7, 4, 0.4, and -3 cm(2) for African Americans and 13, 7, 3, 1, and -15 cm(2) for Hispanics, across the 5 age decades (trend not significant). Mean 5-year increases in SAT areas in women were 88, 46, 19, 17, and 14 cm(2) for African Americans and 53, 20, 17, 12, and 1 cm(2) for Hispanics, across the 5 age decades (P < 0.05 for both). Similar trends have been observed in men. CONCLUSIONS Accumulation of abdominal fat is greatest in young adulthood. These data may be useful in identifying subgroups at risk of type 2 diabetes.

摘要

目的 描述内脏脂肪组织(VAT)和皮下脂肪组织(SAT)面积的5年变化情况。研究设计与方法 对年龄在20 - 69岁、按10岁年龄分组的非裔美国人(n = 389)和西班牙裔美国人(n = 844),每隔5年通过腹部计算机断层扫描测量VAT和SAT的绝对变化。结果 在5个年龄十年中,非裔美国女性VAT面积的平均5年增加量分别为18、7、4、0.4和 - 3平方厘米,西班牙裔女性分别为13、7、3、1和 - 15平方厘米(趋势无统计学意义)。非裔美国女性SAT面积的平均5年增加量分别为88、46、19、17和14平方厘米,西班牙裔女性分别为53、20、17、12和1平方厘米(两者均P < 0.05)。男性中也观察到类似趋势。结论 腹部脂肪堆积在成年早期最为明显。这些数据可能有助于识别有2型糖尿病风险的亚组人群。

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