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β地中海贫血患者的心脏黏液瘤伴髓外造血。

Cardiac myxoma showing extramedullary hematopoiesis in a patient with beta thalassemia.

作者信息

Joukhadar Rene, De Las Casas Luis E, Lalude Omosalewa, Gough David

机构信息

Department of Internal Medicine, Texas Tech University Health Sciences Center, El Paso, TX, USA.

出版信息

South Med J. 2009 Jul;102(7):769-71. doi: 10.1097/SMJ.0b013e3181a8240c.

Abstract

A 52-year-old woman presented with recurrent episodes of chest pain, shortness of breath, palpitations, and fatigue for three months. Her past medical history was significant for chronic anemia. Physical examination revealed a pansystolic murmur radiating to the left axilla. Her admission workup showed microcytic anemia. Her serum creatinine and iron studies were within normal limits and her hemoglobin electrophoresis pattern was that of beta thalassemia minor. Two-dimensional echocardiography showed a multilobulated mobile mass attached to the mitral annulus at the base of the anterior mitral valve leaflet. The patient underwent surgical resection of the mass. Pathology examination revealed a cardiac myxoma with conspicuous foci of extramedullary hematopoiesis.

摘要

一名52岁女性,三个月来反复出现胸痛、气短、心悸和疲劳症状。她既往有慢性贫血病史。体格检查发现全收缩期杂音向左腋窝传导。入院检查显示小细胞贫血。她的血清肌酐和铁代谢检查结果在正常范围内,血红蛋白电泳图谱显示为轻度β地中海贫血。二维超声心动图显示一个多叶状活动肿物附着于二尖瓣前叶瓣叶基部的二尖瓣环处。该患者接受了肿物手术切除。病理检查显示为心脏黏液瘤,伴有明显的髓外造血灶。

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