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心房黏液瘤:一种导致红细胞沉降率升高和贫血的罕见但已被充分描述的病因。

Atrial myxoma: a rare but well-described cause of increased erythrocyte sedimentation rate and anaemia.

作者信息

Ekström Mattias, Svenarud Peter

机构信息

Department of Cardiology, Karolinska Institutet, Stockholm, Sweden.

Department of Cardiovascular Surgery and Anesthesiology, Karolinska University Hospital, Solna, Stockholm, Sweden.

出版信息

BMJ Case Rep. 2015 May 12;2015:bcr2015209820. doi: 10.1136/bcr-2015-209820.

Abstract

A 56-year-old woman visited her general practitioner 12 months prior with eczema. Blood samples showed anaemia, a haemoglobin level of 105 g/L and a high erythrocyte sedimentation rate (ESR) of 80 mm. Her eczema was diagnosed as discoid lupus erythaematosus but there were no signs of systemic lupus erythaematosus. Extensive investigations were made including testing of serial blood samples, repeated examinations by specialists in dermatology, rheumatology and gynaecology, and several X-rays including CT of the chest and the abdomen, all without finding a reasonable underlying diagnosis. One year later, the patient presented with dyspnoea associated with effort and body position; she was sent for echocardiography, which showed an atrial myxoma filling almost the whole left atrium and affecting the mitral valve. She was treated with urgent surgical removal and now, 6 weeks postsurgery, has fully recovered. She no longer has dyspnoea, her haemoglobin level and ESR have normalised, and the eczema has almost disappeared.

摘要

一名56岁女性在12个月前因湿疹就诊于她的全科医生。血液样本显示贫血,血红蛋白水平为105g/L,红细胞沉降率(ESR)高达80mm。她的湿疹被诊断为盘状红斑狼疮,但无系统性红斑狼疮的迹象。进行了广泛的检查,包括连续血液样本检测、皮肤科、风湿病科和妇科专家的反复检查,以及包括胸部和腹部CT在内的多项X光检查,均未找到合理的潜在诊断。一年后,患者出现与活动及体位相关的呼吸困难;她被送去做超声心动图检查,结果显示一个心房黏液瘤几乎填满整个左心房并影响二尖瓣。她接受了紧急手术切除,现在术后6周已完全康复。她不再有呼吸困难,血红蛋白水平和ESR已恢复正常,湿疹也几乎消失。

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