Gönül Ipek Işik, Cakr Asl, Sözen Sinan, Ataoglu Omür, Alkibay Turgut
Department of Pathology, Gazi University School of Medicine.
South Med J. 2009 Jul;102(7):754-7. doi: 10.1097/SMJ.0b013e3181a819c1.
The coexistence of multiple and synchronous primary neoplasms in the genitourinary system has rarely been described in the literature. To our knowledge, this is the first report of a very rare tumor, a "tubulocystic carcinoma," simultaneously occurring with micropapillary urothelial carcinoma in the bladder and clear cell type renal cell carcinoma in the same kidney. Tubulocystic carcinoma is a recently entitled tumor. It had been thought to arise from the distal collecting duct for a period of time and was therefore named as a low-grade collecting duct carcinoma. Microscopically, the tumor is defined as being tubulocystic or having tubulopapillary architecture and a low nuclear grade with hobnail morphology. Its progression and treatment protocol are uncertain.
泌尿生殖系统中多种原发性肿瘤同时并存的情况在文献中鲜有描述。据我们所知，本文首次报道了一种极为罕见的肿瘤——“管状囊性癌”，它与膀胱微乳头型尿路上皮癌以及同一肾脏中的透明细胞型肾细胞癌同时发生。管状囊性癌是一种最近才命名的肿瘤。曾有一段时间它被认为起源于远端集合管，因此被命名为低级别集合管癌。在显微镜下，该肿瘤被定义为具有管状囊性或管状乳头结构，且核级别较低，伴有鞋钉样形态。其进展和治疗方案尚不确定。
