Ishioka Priscila, Marques Sílvio Alencar, Hirai Amélia Toyomi, Marques Mariangela E A, Hirata Sérgio Henrique, Yamada Sérgio
Departamento de Dermatologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brasil.
Cad Saude Publica. 2009 May;25(5):965-71. doi: 10.1590/s0102-311x2009000500003.
Precancerous lesions and skin cancer are infrequent in Asians, and have received little documentation in the literature. Brazil has the world's largest contingent of Japanese immigrants and their descendants, and 70% live in the State of São Paulo. The prevalence of such skin lesions in Japanese-Brazilians is unknown. This study aimed to assess the prevalence of actinic keratoses and non-melanoma skin cancer in first and second-generation Japanese-Brazilians over 30 years of age, without miscegenation, living in the city of Bauru, São Paulo State, in 2006. Of the 567 Japanese-Brazilians that underwent dermatological examination, actinic keratosis was diagnosed in 76, with a mean age of 68.9 years, and a single case of basal cell carcinoma was detected in a 39-year-old female patient. In Japan, prevalence of actinic keratosis varies from 0.76% to 5%, and the incidence of non-melanoma skin cancer is 1.2 to 5.4/100 thousand. Japanese-Brazilians from Bauru showed a 13.4% prevalence of actinic keratoses and earlier age at onset. Proximity to the Equator and a history of farming contribute to these higher rates. Presence of solar melanosis was associated with a 1.9-fold risk of developing actinic keratosis.
癌前病变和皮肤癌在亚洲人中并不常见，在文献中的记载也很少。巴西拥有世界上最大的日本移民及其后裔群体，其中70%生活在圣保罗州。日裔巴西人这类皮肤病变的患病率尚不清楚。本研究旨在评估2006年居住在圣保罗州包鲁市、年龄超过30岁、无混血的第一代和第二代日裔巴西人中光化性角化病和非黑素瘤皮肤癌的患病率。在接受皮肤科检查的567名日裔巴西人中，76人被诊断为光化性角化病，平均年龄为68.9岁，在一名39岁女性患者中检测到1例基底细胞癌。在日本，光化性角化病的患病率在0.76%至5%之间，非黑素瘤皮肤癌的发病率为1.2至5.4/10万。来自包鲁的日裔巴西人光化性角化病的患病率为13.4%，且发病年龄更早。靠近赤道和务农史导致了这些较高的发病率。日光性黑变病的存在与发生光化性角化病的风险增加1.9倍有关。
