Iwasaki Motoki, Mameri Cecilia Polidoro, Hamada Gerson Shigueaki, Tsugane Shoichiro
Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan.
Eur J Cancer Prev. 2008 Feb;17(1):1-8. doi: 10.1097/CEJ.0b013e32811080df.
We investigated secular trends in cancer mortality among first-generation Japanese-Brazilians in the state of São Paulo between 1979 and 2001. Results were compared with those for Japanese living in Japan and Brazilians living in the state of São Paulo. We used mortality data for three periods, 1979-1981, 1989-1991, and 1999-2001, and population data from Brazilian censuses in 1980, 1991, and 2000 for Japanese-Brazilians. Available mortality and population data for Japanese living in Japan and Brazilians living in the state of São Paulo corresponding to those for Japanese-Brazilians were obtained. Age-standardized mortality rates for Japanese-Brazilians and standardized mortality ratios based on mortality of Japanese living in Japan in 1980 for the three different periods and populations were calculated. We observed a decreasing trend for stomach cancer and increasing trends for colon, breast and prostate cancer over the 20 years in all three populations. Standardized mortality ratios for stomach cancer in Japanese-Brazilians declined to approximately those of Japanese living in Japan. Although standardized mortality ratios from colon, breast and prostate cancer in Japanese-Brazilians increased over the last 20 years, those for colon cancer were similar to the Japanese living in Japan whereas those for breast and prostate cancer (208 and 423 in 2000, respectively) appeared to be intermediate between those for Japanese living in Japan (152 and 208 in 2000, respectively) and Brazilians living in the state of São Paulo (281 and 536 in 2000, respectively). Standardized mortality ratios for liver and lung cancer increased in Japanese living in Japan over the last 20 years but no increasing trend was observed for Japanese-Brazilians, except for liver cancer in men, and standardized mortality ratios in Japanese-Brazilians seemed to be similar to the Brazilians living in the state of São Paulo. Secular trends in mortality confirm the relative importance of environment in the development of cancer.
我们调查了1979年至2001年间圣保罗州第一代日裔巴西人的癌症死亡率长期趋势。将结果与生活在日本的日本人以及生活在圣保罗州的巴西人的结果进行了比较。我们使用了三个时期（1979 - 1981年、1989 - 1991年和1999 - 2001年）的死亡率数据，以及1980年、1991年和2000年巴西人口普查中关于日裔巴西人的人口数据。获取了与日裔巴西人相对应的生活在日本的日本人以及生活在圣保罗州的巴西人的可用死亡率和人口数据。计算了三个不同时期和人群中日裔巴西人的年龄标准化死亡率以及基于1980年生活在日本的日本人死亡率的标准化死亡比。我们观察到在这20年中，所有三个人群的胃癌死亡率呈下降趋势，结肠癌、乳腺癌和前列腺癌死亡率呈上升趋势。日裔巴西人胃癌的标准化死亡比下降至与生活在日本的日本人大致相同。尽管日裔巴西人结肠癌、乳腺癌和前列腺癌的标准化死亡比在过去20年中有所上升，但结肠癌的标准化死亡比与生活在日本的日本人相似，而乳腺癌和前列腺癌（2000年分别为208和423）的标准化死亡比似乎介于生活在日本的日本人（2000年分别为152和208）和生活在圣保罗州的巴西人（2000年分别为281和536）之间。过去20年中，生活在日本的日本人肝癌和肺癌的标准化死亡比有所上升，但日裔巴西人除男性肝癌外未观察到上升趋势，日裔巴西人的标准化死亡比似乎与生活在圣保罗州的巴西人相似。死亡率的长期趋势证实了环境在癌症发生发展中的相对重要性。
