Department of Polymer Science and Engineering, Key Laboratory of Macromolecular Synthesis and Functionalization, Ministry of Education, Zhejiang University, Hangzhou 310027, China.
J Mater Sci Mater Med. 2009 Nov;20(11):2259-65. doi: 10.1007/s10856-009-3785-2. Epub 2009 Jun 2.
A novel biocomposite of carbon fiber (CF) reinforced hydroxyapatite (HA)/polylactide (PLA) was prepared by hot pressing a prepreg which consisting of PLA, HA and CF. The prepreg was manufactured by solvent impregnation process. Polymer resin PLA dissolved with chloroform was mixed with HA. After reinforcement CF bundle was impregnated in the mixture, the solvent was dried completely and subsequently hot-pressed uniaxially under a pressure of 40 MPa at 170 degrees C for 20 min. A study was carried out to investigate change in mechanical properties of CF/HA/PLA composites before and after degradation in vitro. The composites have excellent mechanical properties. A peak showed in flexural strength, flexural modulus and shear strength aspects, reaching up 430 MPa, 22 GPa, 212 MPa, respectively, as the HA content increased. Degraded in vitro for 3 months, the flexural strength and flexural modulus of the CF/HA/PLA fell 13.2% and 5.4%, respectively, while the shear strength of the CF/HA/PLA composites remains at the 190 MPa level. The SEM photos showed that there were gaps between the PLA matrix and CF after degradation. Water uptake increased to 5%, but the mass loss rate was only 1.6%. The pH values of the PBS dropped less than 0.1. That's because the alkaline of HA neutralize the acid degrades from PLA, which can prevent the body from the acidity harm.
一种新型碳纤维（CF）增强羟基磷灰石（HA）/聚乳酸（PLA）生物复合材料是通过热压预浸料制备的，预浸料由 PLA、HA 和 CF 组成。预浸料是通过溶剂浸渍工艺制造的。将溶解在氯仿中的聚合物树脂 PLA 与 HA 混合。在 CF 束浸渍在混合物中后，完全干燥溶剂，然后在 170°C 下在 40 MPa 的压力下单向热压 20 分钟。研究了体外降解前后 CF/HA/PLA 复合材料力学性能的变化。该复合材料具有优异的力学性能。随着 HA 含量的增加，在弯曲强度、弯曲模量和剪切强度方面出现峰值，分别达到 430MPa、22GPa 和 212MPa。体外降解 3 个月后，CF/HA/PLA 的弯曲强度和弯曲模量分别下降了 13.2%和 5.4%，而 CF/HA/PLA 复合材料的剪切强度仍保持在 190MPa 水平。SEM 照片显示，降解后 PLA 基体与 CF 之间存在间隙。吸水率增加到 5%，但质量损失率仅为 1.6%。PBS 的 pH 值下降不到 0.1。这是因为 HA 的碱性中和了 PLA 降解产生的酸，从而可以防止身体受到酸性伤害。
