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不同水平日粮补硒后骆驼血液和器官中硒的分布。

Selenium distribution in camel blood and organs after different level of dietary selenium supplementation.

机构信息

United Arab Emirates University, Al-Ain, United Arab Emirates.

出版信息

Biol Trace Elem Res. 2010 Jan;133(1):34-50. doi: 10.1007/s12011-009-8410-1. Epub 2009 Jun 2.

Abstract

Eight young female camels shared in four groups of two 2 years received a basal diet enriched respectively with 0, 2, 4, and 8 mg selenium under sodium selenite form for 64 days. Feed intake was assessed daily; blood samples were taken on weekly basis. One camel from each group was killed at the end of the experiment. Se concentration in serum was increased significantly in the supplemented groups with an average of 176.3 +/- 18.0 ng/mL in the control group, 382.7 +/- 107.6 in the group receiving 2 mg Se, 519.8 +/- 168.4 in the group receiving 4 mg Se, and 533.4 +/- 158.6 in the group receiving 8 mg Se daily. For glutathione peroxidase (GSH-Px) activity, the control group (51.0 IU/g Hb) and the group receiving 2 mg (50.5 IU/g Hb) were significantly different than groups receiving 4 and 8 mg (respectively, 65.9 and 76.1 IU/g Hb). No significant variation occurred for vitamin E (mean, 0.56 +/- 0.23 ng/mL). Significant correlation between serum Se and GSH-Px was reported. Kidney was the richest organ in selenium followed by lung, spleen, and liver, but the increase in supplemented groups was more marked in liver and kidney. The hair seemed to be the best indicator of selenium intake in camel.

摘要

8 头 2 岁雌性小骆驼被分为 4 组,每组 2 头,4 组分别饲喂基础日粮添加 0、2、4、8mg 亚硒酸钠的日粮,共 64 天。每天评估采食量;每周采集血样。试验结束时每组处死 1 头骆驼。血清硒浓度在补充组中显著增加,对照组平均为 176.3±18.0ng/mL,2mgSe 组为 382.7±107.6ng/mL,4mgSe 组为 519.8±168.4ng/mL,8mgSe 组为 533.4±158.6ng/mL。谷胱甘肽过氧化物酶(GSH-Px)活性方面,对照组(51.0IU/gHb)和 2mgSe 组(50.5IU/gHb)与 4mgSe 和 8mgSe 组(分别为 65.9IU/gHb 和 76.1IU/gHb)差异显著。维生素 E 没有显著变化(均值为 0.56±0.23ng/mL)。报道了血清硒与 GSH-Px 之间存在显著相关性。硒在肾脏中含量最丰富,其次是肺、脾和肝,但补充组在肝和肾中的含量增加更为明显。毛发似乎是骆驼硒摄入量的最佳指标。

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