McGowan B, Bennett K, Barry M, Owens M, O'Connor M
Department of Pharmacology and Therapeutics, Trinity Centre for Health Sciences, St James's Hospital, James's St, Dublin 8.
Ir Med J. 2009 Mar;102(3):73-6.
There are approximately 6,300 people in Ireland with a diagnosis of Chronic Obstructive Pulmonary Disease (COPD) and with a fast growing elderly population the incidence of COPD is likely to increase. This study examines the prescribing patterns of medicines dispensed for the management Asthma/COPD in patients over the age of 35 years using the HSE-Primary Care Reimbursement Services (PCRS) prescribing databases. The HSE-PCRS pharmacy claims data, which covers all those over 70 years of age and means tested for those less than 70 years, was analysed for the years 2005/2006. Approximately 26,548 (17.9%) of patients who were prescribed a respiratory drug received inhaled short-acting beta2 agonists in combination with a regular standard-dose inhaled corticosteroid. A further 5,044 (3.4%) were also prescribed a regular inhaled long-acting beta2 agonist (salmeterol or formoterol). A total of 2506 patients (6.2%) on combination therapy were co-prescribed four different anti-asthmatic treatments inclusive of oral prednisolone. A small proportion of the patients prescribed a respiratory drug were co-prescribed nicotine replacement therapy (n = 5177, 3.5%). In total there were 9,728 (6.2%) patients prescribed a mucolytic drug in combination with a respiratory drug and the rate of co-prescribing with antibiotics was 22%. COPD is a debilitating disease that is primarily caused by smoking and is therefore largely preventable. The HSE-PCRS pharmacy claims data is a valuable tool for helping to assess the burden of this disease in the Irish context.
爱尔兰约有6300人被诊断患有慢性阻塞性肺疾病(COPD),且随着老年人口的快速增长,COPD的发病率可能会上升。本研究利用健康服务执行局初级保健报销服务(PCRS)的处方数据库,调查了35岁以上患者中用于治疗哮喘/COPD的药物处方模式。分析了2005/2006年健康服务执行局PCRS药房的报销数据,该数据涵盖了所有70岁以上的人群以及对70岁以下人群进行的经济状况调查。在开具了呼吸系统药物的患者中,约26548人(17.9%)接受了吸入性短效β2激动剂与常规标准剂量吸入性糖皮质激素的联合治疗。另有5044人(3.4%)还开具了常规吸入性长效β2激动剂(沙美特罗或福莫特罗)。在接受联合治疗的2506名患者(6.2%)中,同时开具了包括口服泼尼松龙在内的四种不同抗哮喘治疗药物。开具呼吸系统药物的患者中有一小部分同时开具了尼古丁替代疗法(n = 5177,3.5%)。总共有9728名患者(6.2%)在开具呼吸系统药物的同时还开具了黏液溶解剂,与抗生素联合开具的比例为22%。COPD是一种使人衰弱的疾病,主要由吸烟引起,因此在很大程度上是可以预防的。健康服务执行局PCRS药房的报销数据是帮助评估爱尔兰境内这种疾病负担的宝贵工具。