恒河猴（猕猴属）的高危妊娠：一例异位腹腔妊娠并足月分娩活婴，以及一例妊娠期糖尿病并发先兆子痫。
High-risk pregnancy in rhesus monkeys (Macaca mulatta): a case of ectopic, abdominal pregnancy with birth of a live, term infant, and a case of gestational diabetes complicated by pre-eclampsia.
作者信息
Krugner-Higby Lisa, Luck Melissa, Hartley Deborah, Crispen Heather M, Lubach Gabriele R, Coe Christopher L
机构信息
Research Animal Resources Center, University of Wisconsin-Madison, Madison, WI, USA.
出版信息
J Med Primatol. 2009 Aug;38(4):252-6. doi: 10.1111/j.1600-0684.2009.00349.x. Epub 2009 May 12.
BACKGROUND
Cases of abdominal pregnancy, in the form of intra-abdominal mummified fetuses, have been described in nonhuman primates. Gestational diabetes and pre-eclampsia are common pregnancy complications in women.
METHODS
Two timed-bred rhesus monkeys had high-risk pregnancies, an abdominal pregnancy with delivery of a live term infant, and a case of gestational diabetes that later developed pre-eclampsia.
RESULTS
The monkey that had abdominal pregnancy later died from septic peritonitis. The monkey had a colonic adenocarcinoma that may have allowed leakage of intestinal contents into the abdomen. Her infant was fostered to another female and survived. The monkey with gestational diabetes and pre-eclampsia was treated with a regimen similar to that used in women, and a live infant was delivered at day 157 of gestation by Caesarian section.
CONCLUSION
These cases underscore the value of timed-breeding and the similarities between pregnancy complications in women and in nonhuman primates.
背景
在非人灵长类动物中已描述过腹腔妊娠病例，表现为腹腔内胎儿木乃伊化。妊娠期糖尿病和先兆子痫是女性常见的妊娠并发症。
方法
两只定时配种的恒河猴经历了高危妊娠，其中一只为腹腔妊娠并分娩出一名足月活婴，另一只患有妊娠期糖尿病，后来发展为先兆子痫。
结果
发生腹腔妊娠的猴子后来死于感染性腹膜炎。这只猴子患有结肠腺癌，可能导致肠内容物漏入腹腔。她的婴儿由另一只雌性猴子抚养并存活下来。患有妊娠期糖尿病和先兆子痫的猴子接受了与女性相似的治疗方案，并在妊娠第157天通过剖宫产分娩出一名活婴。
结论
这些病例强调了定时配种的价值以及女性和非人灵长类动物妊娠并发症之间的相似性。
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