苄基紫精对大鼠肝脏脂肪酸组成的影响。
Effect of benzyl viologen on the fatty acid composition of rat liver.
作者信息
Ruiz-Gutierrez V, Muriana F J, Quintero F J
机构信息
Instituto de la Grasa y sus Derivados (C.S.I.C.), Sevilla, Spain.
出版信息
Toxicology. 1991;69(2):199-207. doi: 10.1016/0300-483x(91)90231-o.
The influence of subacute treatment with benzyl viologen (a stimulator of free radical production in cells) on the fatty acid content of rat liver has been analyzed. Lipid storage, essentially characterized by lamellated inclusions, developed as we reported previously (Muriana et al., Exp. Pathol., 32 (1987) 65-72). A substantial increase in liver total lipid, phospholipids and triacylglycerols was found during viologen treatment in rats. The composition in fatty acids was profoundly influenced by the experimental conditions, but to different degrees in different lipid classes.
分析了用苄基紫精（一种细胞内自由基产生的刺激剂）进行亚急性处理对大鼠肝脏脂肪酸含量的影响。如我们之前所报道的（Muriana等人，《实验病理学》，32(1987)65 - 72），脂质储存主要表现为层状包涵体。在给大鼠使用紫精处理期间，发现肝脏总脂质、磷脂和三酰甘油显著增加。脂肪酸组成受到实验条件的深刻影响，但在不同脂质类别中的影响程度不同。
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