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37至1200日龄雌性和雄性大鼠肝脏脂质及331至1200日龄心脏脂质中脂质组分和总脂肪酸的年龄相关性变化(肝脏)。

Age-related changes of lipid fractions and total fatty acids in liver lipids and heart lipids of female and male rats aged 37-1200 days (liver) and 331-1200 days (heart).

作者信息

Murawski U, Kriesten K, Egge H

机构信息

Institute of Physiological Chemistry, University of Bonn, FRG.

出版信息

Comp Biochem Physiol B. 1990;96(2):271-89. doi: 10.1016/0305-0491(90)90375-4.

DOI:10.1016/0305-0491(90)90375-4
PMID:2361362
Abstract
  1. Total lipids and the lipid fractions cholesterol ester, triacylglycerol, free cholesterol, free fatty acids and phospholipids, as well as the fatty acid patterns of total lipids, were measured in liver homogenates of female and male rats (Wistar SPF, strain Hannover) aged 37-1213 days. 2. The same parameters were measured in the apex of the heart in female and male rats aged 331-1213 days. 3. All parameters were monitored every 49th day. Five female and five male animals were used in each experiment. 4. The lipid fractions in liver showed a positive linear regression vs age, whereas all lipids in rat heart showed a negative regression vs age in both sexes. 5. The significance of regression vs age of fatty acids was much less than that in the lipid fractions of liver and heart of these animals.
摘要
  1. 在37 - 1213日龄的雌性和雄性大鼠(Wistar SPF,汉诺威品系)的肝脏匀浆中,测定了总脂质及其脂质组分胆固醇酯、三酰甘油、游离胆固醇、游离脂肪酸和磷脂,以及总脂质的脂肪酸模式。2. 在331 - 1213日龄的雌性和雄性大鼠的心脏尖部测定了相同参数。3. 每隔49天监测所有参数。每个实验使用5只雌性和5只雄性动物。4. 肝脏中的脂质组分与年龄呈正线性回归,而大鼠心脏中的所有脂质在两性中均与年龄呈负回归。5. 脂肪酸与年龄回归的显著性远低于这些动物肝脏和心脏脂质组分中的显著性。

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Age-related changes of lipid fractions and total fatty acids in liver lipids and heart lipids of female and male rats aged 37-1200 days (liver) and 331-1200 days (heart).37至1200日龄雌性和雄性大鼠肝脏脂质及331至1200日龄心脏脂质中脂质组分和总脂肪酸的年龄相关性变化(肝脏)。
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