Unoki Noriyuki, Nishijima Kazuaki, Kita Mihori, Oh Hideyasu, Sakamoto Atsushi, Kameda Takanori, Hayashi Hisako, Yoshimura Nagahisa
Department of Ophthalmology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Retina. 2009 Sep;29(8):1128-33. doi: 10.1097/IAE.0b013e3181a4d2d9.
To report lamellar macular hole formation in four patients with diabetic cystoid macular edema (CME).
A review of the medical records of four patients with diabetic CME in whom lamellar macular hole formation was observed. The morphologic changes of CME, seen using optical coherence tomography (OCT), and best-corrected visual acuity were evaluated.
Lamellar macular hole formation had occurred, as determined by slit-lamp biomicroscopy and OCT. Although the inner retinal layer had disappeared, the outer retinal layer was preserved. On OCT, the reflective line of an epiretinal membrane or a posterior hyaloid membrane was seen on the surface of juxtafoveal retina, and visual acuity remained unchanged in all four patients.
In diabetic patients with CME, the CME occasionally changes spontaneously to a lamellar macular hole. Although the central cystoid space disappears and foveal thickness decreases after this transformation, visual acuity may be little affected as long as the structure of the outer retina remains intact.
报告4例糖尿病性黄斑囊样水肿（CME）患者中出现的板层黄斑裂孔形成情况。
回顾4例观察到板层黄斑裂孔形成的糖尿病性CME患者的病历。使用光学相干断层扫描（OCT）评估CME的形态学变化以及最佳矫正视力。
通过裂隙灯生物显微镜检查和OCT确定发生了板层黄斑裂孔形成。虽然视网膜内层消失，但外层视网膜得以保留。在OCT上，在黄斑旁视网膜表面可见视网膜前膜或后玻璃体膜的反射线，且4例患者的视力均保持不变。
在患有CME的糖尿病患者中，CME偶尔会自发转变为板层黄斑裂孔。尽管这种转变后中央囊样间隙消失且黄斑厚度降低，但只要外层视网膜结构保持完整，视力可能受影响较小。
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