Cui Hongguang, Hu Rongrong, Zhang Yingying, Lou Dinghua
Department of Ophthalmology, First Affiliated Hospital, Zhejiang University, Hangzhou, China.
Can J Ophthalmol. 2009 Jun;44(3):274-8. doi: 10.3129/i08-121.
This study compares the visual performance of spherical and aspherical intraocular lenses (IOLs) by measuring higher-order aberration and contrast sensitivity (CS) values.
Prospective controlled study.
Fifty-seven patients with age-related cataract (61 eyes).
Patients were randomly allocated to 1 of 3 groups and implanted with either aspherical IOLs, Acrysof IQ (SN60WF) or Tecnis Z9001, or a spherical IOL, Acrysof Natural. Patients underwent routine examinations, including visual acuity, slit-lamp checks, and best-corrected visual acuity (BCVA), as well as measurement of higher-order aberrations and CS values, preoperatively and at 1 week, 1 month, and 2 months postoperatively.
All the patients had a BCVA better than 20/30 postoperatively. The spherical aberrations of the IQ group and Tecnis group were both lower than in the Natural (control) group (IQ: p < 0.05; Tecnis: p < 0.05); there was no significant difference in coma and higher-order aberration. No statistically significant difference was found in spherical aberration, coma, or higher-order aberration between the IQ and Tecnis groups. Under glare conditions, the CS values of the 2 aspherical IOLs were obviously better (IQ: p < 0.05; Tecnis: p < 0.05) than the CS value of the spherical IOL group at low frequency (IQ: 6.3 degrees, Tecnis: 4.0 degrees); under non-glare conditions there was a significant difference in CS values between the aspherical IOL groups and the control group (IQ: p < 0.01; Tecnis: p < 0.01) at low frequency (both 6.3 degrees). There was no statistical difference between the IQ and the Tecnis groups with or without glare.
An aspherical IOL can effectively reduce spherical aberration after cataract surgery, enhance CS values, and improve visual quality compared with traditional spherical IOLs for age-related cataract. However, there was no statistically significant difference in postoperative aberration and CS values between the Acrysof IQ and Tecnis Z9001 aspherical IOLs.
本研究通过测量高阶像差和对比敏感度（CS）值，比较球面和非球面人工晶状体（IOL）的视觉性能。
前瞻性对照研究。
57例年龄相关性白内障患者（61只眼）。
将患者随机分为3组，分别植入非球面IOL（Acrysof IQ，SN60WF或Tecnis Z9001）或球面IOL（Acrysof Natural）。患者在术前以及术后1周、1个月和2个月接受常规检查，包括视力、裂隙灯检查和最佳矫正视力（BCVA），以及高阶像差和CS值的测量。
所有患者术后BCVA均优于20/30。IQ组和Tecnis组的球差均低于Natural（对照）组（IQ：p < 0.05；Tecnis：p < 0.05）；在彗差和高阶像差方面无显著差异。IQ组和Tecnis组之间在球差、彗差或高阶像差方面未发现统计学上的显著差异。在眩光条件下，两种非球面IOL在低频（IQ：6.3度，Tecnis：4.0度）时的CS值明显优于球面IOL组（IQ：p < 0.05；Tecnis：p < 0.05）；在非眩光条件下，非球面IOL组与对照组在低频（均为6.3度）时的CS值存在显著差异（IQ：p < 0.01；Tecnis：p < 0.01）。有无眩光情况下，IQ组和Tecnis组之间均无统计学差异。
与传统球面IOL相比，非球面IOL可有效降低白内障手术后的球差，提高CS值，改善年龄相关性白内障患者的视觉质量。然而，Acrysof IQ和Tecnis Z9001非球面IOL术后像差和CS值之间无统计学显著差异。
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