Parkhomets T I, Slatvinskaia E A, Ruchko M V, Kucherenko N E
Ukr Biokhim Zh (1978). 1991 Jul-Aug;63(4):107-10.
It is established, that low doses of X-ray irradiation have affected activation of lipid peroxidation (LPO) in immunocompetent cells of the spleen and thymus. The amount of malonic dialdehyde (MDA) in lymphocytes of spleen and thymocytes increases 2 times twenty-four hours after animals' irradiation by X-rays in a dose of 0.5 Gy; when a dose grows to 1.0 Gy, the MDA content in the spleen lymphocytes increases from the 1st to the 6th days and in thymocytes from the 1st to the 3d days reaching its maximum at the 3d day. MDA accumulation in the immunocompetent cells of irradiated animals varies depending on the method of lipid peroxidation initiation.
已经确定,低剂量的X射线辐射会影响脾脏和胸腺免疫活性细胞中脂质过氧化(LPO)的激活。在动物接受0.5 Gy剂量的X射线照射24小时后,脾脏淋巴细胞和胸腺细胞中的丙二醛(MDA)含量增加2倍;当剂量增加到1.0 Gy时,脾脏淋巴细胞中的MDA含量在第1天至第6天增加,胸腺细胞中的MDA含量在第1天至第3天增加,并在第3天达到最大值。受辐照动物免疫活性细胞中MDA的积累因脂质过氧化引发方法的不同而有所差异。