[用喹啉-2测定照射大鼠脾脏淋巴细胞中游离钙离子水平的升高]
[Increase in free Ca2+ level determined by quin-2 in spleen lymphocytes from irradiated rats].
作者信息
Ruchko M V, Slatvinskaia E A, Matyshevskaia O P, Kucherenko N E
出版信息
Ukr Biokhim Zh (1978). 1990 Jul-Aug;62(4):110-3.
The output of lymphocytes, obtained on a ficoll-verografin gradient and intracellular free Ca2+ concentration were studied in the rat spleen 1, 3 and 6 days after X-ray irradiation in a dose of 0.5 Gy. The amount of lymphocytes decreased by 30% a day after irradiation and turned to the control level 3 days after exposure of animals. Free Ca2+ concentration remains abnormally high during all the examined period, increasing to 411 nM a day after irradiation and approaching to the control value 6 days after irradiation.
研究了在0.5 Gy X射线照射后1、3和6天，大鼠脾脏中通过菲可-泛影葡胺梯度分离获得的淋巴细胞输出量以及细胞内游离Ca2+浓度。照射后一天淋巴细胞数量减少了30%，在动物受照3天后恢复到对照水平。在整个检查期间，游离Ca2+浓度一直异常高，照射后一天增加到411 nM，照射6天后接近对照值。
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