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[Effect of the substances "Ammivit" and "cerloplasmin" on lipid peroxidation products level and of antioxidant system indicators under irradiation].

作者信息

Hadiliia O P, Andriĭchuk T R, Merkulov S P, Ostapchenko L I, Kucherenko M E

机构信息

Taras Shevchenko Kyiv National University, Ukraine.

出版信息

Ukr Biokhim Zh (1999). 2002 Jan-Feb;74(1):97-100.

Abstract

It has been shown, that the total X-ray irradiation in the dozes of 0.5 and 1 Gy influences on the content of lipid peroxidation products and enzymatic activity of antioxidant system in rat spleen and thymus cells. The influence of preparations "AMMIVIT" and "Ceruloplasmin" on these processes is investigated also. So, the animals feeding by the vitamin concentrate "AMMIVIT" have lead to increase of MDA level (a final product of lipid peroxidation) and the overactivity of some antioxidant enzymes in rat spleen and thymus cells. Injection of the preparation "Ceruloplasmin" to experimental animals up 1 hour before the irradiation has normalized LPO intensity and activity of AO enzymes.

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