Virtue Elena R, Marsh Glenn A, Wang Lin-Fa
CSIRO Livestock Industries, Australian Animal Health Laboratory (AAHL), Geelong, VIC, Australia.
Future Microbiol. 2009 Jun;4(5):537-54. doi: 10.2217/fmb.09.26.
Prior to the emergence of Hendra virus in Australia in 1994, paramyxoviruses were considered to be a taxonomic group of ubiquitous pathogens, consisting primarily of Biosafety Level 2 agents, which possessed narrow host ranges and often caused only mild or preventable diseases in humans and animals. In recent years, a number of Paramyxoviridae members have emerged, including previously unrecognized human pathogens and highly pathogenic zoonoses. The recent emergence of paramyxoviruses in humans suggests that there is an increased incidence of zoonotic transmission between wildlife, livestock and human hosts. This article explores the current body of scientific knowledge, disease burden and knowledge of reservoirs of these emerging paramyxoviruses and provides a comparative review of both older and emerging viruses that have been shown to infect humans.
在1994年澳大利亚出现亨德拉病毒之前，副粘病毒被认为是一类普遍存在的病原体分类群，主要由生物安全2级病原体组成，其宿主范围狭窄，通常仅在人类和动物中引起轻度或可预防的疾病。近年来，出现了一些副粘病毒科成员，包括以前未被认识的人类病原体和高致病性人畜共患病原。副粘病毒最近在人类中的出现表明，野生动物、家畜和人类宿主之间人畜共患传播的发生率有所增加。本文探讨了这些新兴副粘病毒的现有科学知识、疾病负担和宿主知识，并对已被证明可感染人类的新旧病毒进行了比较综述。
