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绿茶和白茶提取物的局部应用可为人类皮肤提供针对模拟太阳光紫外线的防护。

Topical application of green and white tea extracts provides protection from solar-simulated ultraviolet light in human skin.

作者信息

Camouse Melissa M, Domingo Diana Santo, Swain Freddie R, Conrad Edward P, Matsui Mary S, Maes Daniel, Declercq Lieve, Cooper Kevin D, Stevens Seth R, Baron Elma D

机构信息

Department of Dermatology, University Hospitals Case Medical Center Cleveland, OH 44106, USA.

出版信息

Exp Dermatol. 2009 Jun;18(6):522-6. doi: 10.1111/j.1600-0625.2008.00818.x.

DOI:10.1111/j.1600-0625.2008.00818.x
PMID:19492999
Abstract

BACKGROUND

Tea polyphenols have been found to exert beneficial effects on the skin via their antioxidant properties.

AIMS

We sought to determine whether topical application of green tea or white tea extracts would prevent simulated solar radiation-induced oxidative damages to DNA and Langerhans cells that may lead to immune suppression and carcinogenesis.

METHODS

Skin samples were analysed from volunteers or skin explants treated with white tea or green tea after UV irradiation. In another group of patients, the in vivo immune protective effects of green and white tea were evaluated using contact hypersensitivity to dinitrochlorobenzene.

RESULTS

Topical application of green and white tea offered protection against detrimental effects of UV on cutaneous immunity. Such protection is not because of direct UV absorption or sunscreen effects as both products showed a sun protection factor of 1. There was no significant difference in the levels of protection afforded by the two agents. Hence, both green tea and white tea are potential photoprotective agents that may be used in conjunction with established methods of sun protection.

摘要

背景

已发现茶多酚通过其抗氧化特性对皮肤产生有益作用。

目的

我们试图确定局部应用绿茶或白茶提取物是否能预防模拟太阳辐射诱导的对DNA和朗格汉斯细胞的氧化损伤,这些损伤可能导致免疫抑制和致癌作用。

方法

对紫外线照射后用白茶或绿茶处理的志愿者皮肤样本或皮肤外植体进行分析。在另一组患者中,使用对二硝基氯苯的接触性超敏反应评估绿茶和白茶的体内免疫保护作用。

结果

局部应用绿茶和白茶可防止紫外线对皮肤免疫的有害影响。这种保护并非由于直接紫外线吸收或防晒作用,因为两种产品的防晒系数均为1。两种制剂提供的保护水平无显著差异。因此,绿茶和白茶都是潜在的光保护剂,可与既定的防晒方法联合使用。

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