Type 2 iodothyronine deiodinase in human skeletal muscle: new insights into its physiological role and regulation.
作者信息
Larsen P Reed
出版信息
J Clin Endocrinol Metab. 2009 Jun;94(6):1893-5. doi: 10.1210/jc.2009-0791.
Abstract
摘要
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Type 2 iodothyronine deiodinase in human skeletal muscle: new insights into its physiological role and regulation.人骨骼肌中的2型碘甲状腺原氨酸脱碘酶：对其生理作用和调节的新见解
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[Role of iodothyronine-deiodinase in thyroid hormone mechanisms in animal and human cells].[碘甲状腺原氨酸脱碘酶在动物和人类细胞甲状腺激素机制中的作用]
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Functional brown adipose tissue in healthy adults.健康成年人中的功能性棕色脂肪组织。
N Engl J Med. 2009 Apr 9;360(15):1518-25. doi: 10.1056/NEJMoa0808949.
2
Identification and importance of brown adipose tissue in adult humans.成人棕色脂肪组织的识别及其重要性。
N Engl J Med. 2009 Apr 9;360(15):1509-17. doi: 10.1056/NEJMoa0810780.
3
Cold-activated brown adipose tissue in healthy men.健康男性体内的冷激活棕色脂肪组织
N Engl J Med. 2009 Apr 9;360(15):1500-8. doi: 10.1056/NEJMoa0808718.
4
Type 2 iodothyronine deiodinase in skeletal muscle: effects of hypothyroidism and fasting.骨骼肌中的2型碘甲状腺原氨酸脱碘酶：甲状腺功能减退和禁食的影响。
J Clin Endocrinol Metab. 2009 Jun;94(6):2144-50. doi: 10.1210/jc.2008-2520. Epub 2009 Mar 17.
5
Type 2 deiodinase expression is induced by peroxisomal proliferator-activated receptor-gamma agonists in skeletal myocytes.2型脱碘酶的表达在骨骼肌细胞中由过氧化物酶体增殖物激活受体γ激动剂诱导产生。
Endocrinology. 2009 Apr;150(4):1976-83. doi: 10.1210/en.2008-0938. Epub 2008 Nov 26.
6
Cellular and molecular basis of deiodinase-regulated thyroid hormone signaling.脱碘酶调节甲状腺激素信号传导的细胞和分子基础。
Endocr Rev. 2008 Dec;29(7):898-938. doi: 10.1210/er.2008-0019. Epub 2008 Sep 24.
7
Ectopic brown adipose tissue in muscle provides a mechanism for differences in risk of metabolic syndrome in mice.肌肉中的异位棕色脂肪组织为小鼠代谢综合征风险差异提供了一种机制。
Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2366-71. doi: 10.1073/pnas.0610416104. Epub 2007 Feb 5.
8
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation.胆汁酸通过促进细胞内甲状腺激素激活来诱导能量消耗。
Nature. 2006 Jan 26;439(7075):484-9. doi: 10.1038/nature04330. Epub 2006 Jan 8.
9
Type 2 iodothyronine deiodinase is the major source of plasma T3 in euthyroid humans.2型碘甲状腺原氨酸脱碘酶是甲状腺功能正常的人体内血浆T3的主要来源。
J Clin Invest. 2005 Sep;115(9):2524-33. doi: 10.1172/JCI25083. Epub 2005 Aug 25.
10
The type 2 deiodinase A/G (Thr92Ala) polymorphism is associated with decreased enzyme velocity and increased insulin resistance in patients with type 2 diabetes mellitus.2型脱碘酶A/G（苏氨酸92位突变为丙氨酸）多态性与2型糖尿病患者酶活性降低及胰岛素抵抗增加有关。
J Clin Endocrinol Metab. 2005 Jun;90(6):3472-8. doi: 10.1210/jc.2004-1977. Epub 2005 Mar 29.
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