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[前列腺癌的潜在激素疗法]

[The potential hormonal therapy of prostatic carcinoma].

作者信息

Studer U E, Altwein J, Bartsch G

机构信息

Urologische Universitäts-Klinik Inselspital, Bern, Schweiz.

出版信息

Urologe A. 1991 Sep;30(5):310-6.

PMID:1949440
Abstract

Hormonal manipulation is still the most effective systemic treatment for prostate cancer. The alternatives to orchiectomy are discussed: estrogens, with their known cardiovascular side-effects, and the expensive LH-RH analogues and/or antiandrogens, the success of which depends heavily on the patient's compliance. With more intensive health care and more sensitive methods of diagnosis, not only is the overall number of prostate carcinomas diagnosed increasing, but also the percentage that need not be fatal. The timing of hormonal treatment and selection of patients are increasing in importance.

摘要

激素治疗仍然是前列腺癌最有效的全身治疗方法。本文讨论了睾丸切除术的替代方案:雌激素,其具有已知的心血管副作用;以及昂贵的促黄体生成素释放激素(LH-RH)类似物和/或抗雄激素药物,其成功与否在很大程度上取决于患者的依从性。随着医疗保健的加强和诊断方法的更加灵敏,不仅诊断出的前列腺癌总数在增加,而且无需致命的比例也在增加。激素治疗的时机和患者的选择变得越来越重要。

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