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[电极波形和配置对植入式心脏复律除颤器除颤阈值的影响]

[Influence of waveform and configuration of electrodes on the defibrillation threshold of implantable cardioverter-defibrillators].

作者信息

Block M, Hammel D, Breithardt G

机构信息

Medizinische Klinik und Poliklinik Innere Medizin C, Westfälische Wilhelms-Universität Münster, 48129, Münster.

出版信息

Herzschrittmacherther Elektrophysiol. 1997 Mar;8(1):15-31. doi: 10.1007/BF03042474.

Abstract

The defibrillation threshold (DFT) is no threshold in the true sense. Between energy levels which defibrillate in all cases and energy levels which never defibrillate, a broad range of energies exists which might or might not defibrillate. Thus, the value of the DFT is dependant on the protocol used for its determination. Usually the DFT presents an energy at which the implantable cardioverter-defibrillator (ICD) will defibrillate successfully at a rate of approximately 75%. To achieve a 100% success rate the energy has to be programmed 15 J above the DFT or twice the DFT.Using DFT measurements the energy needed for internal defibrillation could be gradually reduced in the last years. Major break throughs have been the introduction of the biphasic defibrillation waveform and the use of pectorally implanted ICD shells as defibrillation electrodes. The shortening of the defibrillation impulse by the use of lower capacitances could not improve DFTs but allowed to construct ICDs of smaller volume. Addition of a superior vena cava electrode or a subcutaneous array electrode at the left lateral chest to the standard bipolar electrode system (right ventricle, pectoral ICD can) allowed for tri- and quadripolar lead configurations which reduced DFTs on average only slightly but reduced the standard deviation of DFTs significantly and thus helped to avoid high DFTs. Besides building smaller ICDs, reduction of DFTs and thus programming of lower defibrillation ICD energies allows for improved battery longevities and reduced capacitor charging times and thus a lower incidence of syncopes.

摘要

除颤阈值(DFT)在真正意义上并无阈值。在所有情况下均能除颤的能量水平与从未除颤的能量水平之间,存在着一大范围的能量,其可能除颤,也可能无法除颤。因此,DFT的值取决于用于确定它的方案。通常,DFT呈现的是植入式心脏复律除颤器(ICD)以大约75%的成功率成功除颤的能量。为了达到100%的成功率,能量必须设置为比DFT高15焦耳或DFT的两倍。在过去几年中,通过DFT测量,体内除颤所需的能量得以逐渐降低。重大突破包括双相除颤波形的引入以及使用胸壁植入的ICD外壳作为除颤电极。通过使用较低电容来缩短除颤脉冲,虽无法改善DFT,但使得能够制造体积更小的ICD。在标准双极电极系统(右心室、胸壁ICD罐)基础上,在左侧胸部添加一个上腔静脉电极或皮下阵列电极,可实现三极和四极导联配置,这平均仅略微降低了DFT,但显著降低了DFT的标准差,从而有助于避免出现高DFT。除了制造更小的ICD外,降低DFT并因此设置更低的ICD除颤能量,可提高电池寿命,减少电容器充电时间,并因此降低晕厥发生率。

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