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水淋巴疗法治疗乳腺癌治疗相关淋巴水肿的女性:一项随机对照研究。

Aqua lymphatic therapy in women who suffer from breast cancer treatment-related lymphedema: a randomized controlled study.

机构信息

Department of Physical Therapy, "Maccabi Healthcare Services", Netivot, Israel.

出版信息

Support Care Cancer. 2010 Mar;18(3):383-92. doi: 10.1007/s00520-009-0669-4. Epub 2009 Jun 3.

Abstract

BACKGROUND

Lymphedema is an adverse effect of breast cancer surgery. Aqua lymphatic therapy (ALT) is a novel treatment for limb volume reduction.

OBJECTIVE

The aim of this study was to examine whether ALT is a safe method and whether there are differences in adherence, limb volume, and quality of life between women who perform only self-management treatment and women who participate as well in ALT.

DESIGN

Design of the study was single-blind randomized clinical trial.

SETTING

The setting was in a hydrotherapy pool, 1.2 m depth, and a temperature of 32-33 degrees capital ES, Cyrillic.

PATIENTS

Forty-eight women (56 +/- 10 years), with a 12.8% lymphedema relative volume, participated in the study.

INTERVENTION

The control group was instructed to perform the self-management treatment. The study group joined a weekly session of ALT for 3 months in addition to the self-management therapy.

MEASUREMENTS

Adherence was assessed by a self-reported diary, limb volume by a water displacement device, quality of life by the Upper Limb Lymphedema Questionnaire (ULL27), prior to, and after the intervention period.

RESULTS

There was no episode of arm infection or aggravation in limb volume during the study period. ALT had a positive, statistically and clinically significant immediate effect on limb volume but no long-term effect was noted. The adherence rate to ALT was significantly higher than the adherence to self-management therapy. QOL improved in the study group.

CONCLUSION

ALT was found to be a safe method, with high adherence, in treating women who suffer from mild to moderate lymphedema. A significant immediate and insignificant long-term effect on limb volume was noted.

摘要

背景

淋巴水肿是乳腺癌手术后的一种不良反应。水疗淋巴引流(ALT)是一种治疗肢体体积减少的新方法。

目的

本研究旨在检验 ALT 是否为一种安全的方法,以及仅行自我管理治疗的女性与同时行 ALT 治疗的女性在依从性、肢体体积和生活质量方面是否存在差异。

设计

本研究的设计为单盲随机临床试验。

设置

该研究在水深 1.2 米、水温 32-33°C 的水疗池中进行。

患者

48 名女性(56±10 岁),其淋巴水肿相对体积为 12.8%,参与了该研究。

干预

对照组被指导进行自我管理治疗。研究组在自我管理治疗的基础上,每周接受一次 ALT 治疗,共 3 个月。

测量

通过自我报告日记评估依从性,通过水置换装置测量肢体体积,通过上肢淋巴水肿问卷(ULL27)评估生活质量,在干预前后进行测量。

结果

在研究期间,手臂未发生感染或肢体体积加重。ALT 对肢体体积有即刻的、具有统计学意义和临床意义的积极影响,但未观察到长期影响。ALT 的依从率显著高于自我管理治疗的依从率。研究组的生活质量得到改善。

结论

ALT 被发现是一种安全的方法,具有较高的依从性,可用于治疗患有轻度至中度淋巴水肿的女性。它对肢体体积具有即刻的显著影响和长期的不显著影响。

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