Department of Dermatology, University of Montpellier I, Hôpital Saint-Eloi, CHU de Montpellier, Montpellier, France.
J Eur Acad Dermatol Venereol. 2010 Feb;24(2):208-13. doi: 10.1111/j.1468-3083.2009.03305.x. Epub 2009 Jun 2.
Cutaneous lymphoid hyperplasia (CLH or pseudolymphoma) is considered a rare complication occurring in tattoos. We analysed the demographics, clinical features, histological aspects, allergy tests, outcome and therapeutic data of CLH in tattoos performed by a professional in a series of patients.
We conducted a retrospective chart review of seven patients managed in private practice of dermatology all over France from 2001 to 2007.
Reactions occurred within 2 years after tattooing, were non-specific (pruritus, swelling, infiltration) and mainly restricted to red. Photosensitivity was noted in two cases. Histology was characteristic of pseudolymphoma with a T-cell predominance in all cases. Surgery (2 cases) and laser removal (2 cases, CO2 and QS-532 nm) were efficient, while local corticosteroids were not. One patient had spontaneous clinical remission after 2 years of evolution.
This is the largest series of CLH occurring in tattoos. This delayed hypersensitivity reaction may be underestimated and triggered by a specific immunogenic compound of the ink. Its management remains difficult.
皮肤淋巴组织增生（CLH 或假性淋巴瘤）被认为是一种罕见的纹身并发症。我们分析了一组患者中由专业人员进行的纹身相关 CLH 的人口统计学、临床特征、组织学方面、过敏测试、结果和治疗数据。
我们对 2001 年至 2007 年期间在法国私人皮肤科诊所就诊的 7 名患者进行了回顾性图表审查。
反应发生在纹身后 2 年内，是非特异性的（瘙痒、肿胀、浸润），主要局限于红色。两例出现光过敏。所有病例的组织学均具有假性淋巴瘤的特征，以 T 细胞为主。手术（2 例）和激光去除（2 例，CO2 和 QS-532nm）有效，而局部皮质类固醇无效。1 例患者在 2 年的病程后自发出现临床缓解。
这是纹身相关 CLH 的最大系列。这种迟发型超敏反应可能被低估，其触发因素是油墨中的特定免疫原性化合物。其管理仍然困难。
