肾移植后曲霉感染局限于吻合动脉：4例报告

Aspergillus infection limited to the anastomosed artery following renal transplantation: a report of 4 cases.

作者信息

Wang R, Wu J, Wang Y, Huang H, He Q, Chen J

机构信息

Kidney Disease Center, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.

出版信息

Transpl Infect Dis. 2009 Aug;11(4):363-6. doi: 10.1111/j.1399-3062.2009.00402.x. Epub 2009 May 21.

DOI:10.1111/j.1399-3062.2009.00402.x

PMID:19497076

Abstract

We present 4 cases of Aspergillus fumigatus infection limited to the anastomosed artery following renal transplantation. All grafts were nephrectomized. Two patients received 2 weeks of itraconazole therapy; both showing recurrence of pseudoaneurysms following discontinuation of therapy. Another 2 patients received 3 months of itraconazole therapy without recurrence of pseudoaneurysms. Surgical interventions were life saving. Resection of infected tissues and 3 months of antifungal therapy seemed to give better results than shorter antifungal strategies.

摘要

我们报告了4例肾移植后烟曲霉感染局限于吻合动脉的病例。所有移植肾均被切除。2例患者接受了2周的伊曲康唑治疗；两人在治疗中断后均出现假性动脉瘤复发。另外2例患者接受了3个月的伊曲康唑治疗，未出现假性动脉瘤复发。手术干预挽救了生命。切除感染组织并进行3个月的抗真菌治疗似乎比更短疗程的抗真菌策略效果更好。