Osteoporosis is an important medical condition which is expensive in morbidity and mortality. Type I osteoporosis affects women 10-15 years after menopause and involves primarily trabecular bone while Type II, senile osteoporosis, results in hip fractures in both sexes. Lifelong calcium intake and physical activity affect peak bone mass and are instrumental in prevention of osteoporosis. Therapy with fluoride, vitamin D, androgens and diphosphonates have been studied and their results and side effects are reviewed.
骨质疏松症是一种重要的医学病症,在发病率和死亡率方面代价高昂。I型骨质疏松症在绝经后10至15年影响女性,主要累及小梁骨,而II型,即老年性骨质疏松症,则会导致两性髋部骨折。终生钙摄入量和体育活动会影响峰值骨量,对预防骨质疏松症至关重要。已经对氟化物、维生素D、雄激素和双膦酸盐进行了治疗研究,并对其结果和副作用进行了综述。