Kroma Ghazwan, Lopera Jorge, Cura Marco, Suri Rajeev, El-Merhi Fadi, Reading Jerad
Department of Interventional Radiology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, Mail Stop 7800, San Antonio, TX 78229-3900, USA.
J Vasc Interv Radiol. 2009 Jul;20(7):981-6. doi: 10.1016/j.jvir.2009.03.042. Epub 2009 Jun 4.
Creation of a transjugular intrahepatic portosystemic shunt (TIPS) can effectively treat complications of portal hypertension, but excessive shunting can cause life-threatening hepatic encephalopathy and hepatic insufficiency. The present report describes a novel technique that allows for controlled and adjustable flow reduction through the TIPS via partial closure of the shunt with a balloon-mounted covered stent. The method results in clinical improvement of hepatic encephalopathy and hepatic insufficiency and immediate increase in the portosystemic pressure gradient. However, among the four patients described herein, survival beyond 1 year was seen in only one, who underwent liver transplantation after TIPS reduction.
经颈静脉肝内门体分流术（TIPS）的创建可有效治疗门静脉高压症的并发症，但过度分流可导致危及生命的肝性脑病和肝功能不全。本报告描述了一种新技术，该技术可通过使用球囊覆盖支架部分封闭分流来控制和调节经TIPS的血流减少。该方法可使肝性脑病和肝功能不全得到临床改善，并使门体压力梯度立即增加。然而，在本文所述的4例患者中，仅1例存活超过1年，该患者在TIPS血流减少后接受了肝移植。
