Department of Dermatology, Ministry of Health Ankara Diskapi Yildirim Beyazit Education and Research Hospital, Ankara, Turkey.
Eur J Dermatol. 2009 Sep-Oct;19(5):478-80. doi: 10.1684/ejd.2009.0726. Epub 2009 Jun 5.
Treatment of acrodermatitis continua of Hallopeau (ACH) is known to be difficult. A 24-year-old man presented with an 11-year history of recurrent flares of painful pustular and scaly lesions on the distal portion of his fingers and toes, with persistent nail dystrophy. Based on the clinical and histopathological findings, ACH was diagnosed. The patient was treated with topical 8-methoxypsoralen (8-MOP) without occlusion, plus local narrowband ultraviolet B (NB-UVB) phototherapy. The patient did not use any other medication between sessions except topical emollients. Ten weeks later, when the patient had received 20 sessions, almost all the lesions had cleared. We report the first case of ACH which successfully responded to treatment with 8-MOP/NB-UVB.
治疗 Hallopeau 连续性肢端皮炎（ACH）已知是困难的。一名 24 岁男子，因手指和脚趾远端反复发作疼痛性脓疱性和鳞屑性皮损，伴持续性甲营养不良，前来就诊，病史 11 年。根据临床和组织病理学发现，诊断为 ACH。患者接受局部 8-甲氧基补骨脂素（8-MOP）治疗，不采用光封闭，加局部窄谱中波紫外线（NB-UVB）光疗。除局部用保湿剂外，患者在治疗间隙期不使用其他任何药物。10 周后，患者共接受了 20 次治疗，几乎所有皮损都已消退。我们报告首例成功用 8-MOP/NB-UVB 治疗的 ACH 病例。
