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与墨西哥城小儿腹泻相关的肠道病原体

Enteropathogens associated with pediatric diarrhea in Mexico City.

作者信息

Evans D G, Olarte J, DuPont H L, Evans D J, Galindo E, Portnoy B L, Conklin R H

出版信息

J Pediatr. 1977 Jul;91(1):65-8. doi: 10.1016/s0022-3476(77)80446-0.

Abstract

Enteropathogens were investigated as possible agents in pediatric diarrhea occurring in Mexico City during the summer of 1975. Pathogens were identified in 47 (76%) of 62 cases. Rotavirus particles were detected in 16 cases. Enterotoxigenic Escherichia coli was detected in 29 cases; 11 were positive for heat-labile enterotoxin and 18 were positive for only the heat-stable form of enterotoxin. Multiple pathogens were found simultaneously in 15 (24%) of the study population. This study indicates that the etiology of pediatric summertime diarrhea in Mexico City is diverse. ETEC and RV were the most frequently encountered pathogens, yet they frequently occurred together and with other pathogens. ST-only strains of toxigenic E. coli were as frequently recovered as LT-E. coli suggesting that both forms of ETEC must be sought in future field studies.

摘要

对1975年夏季在墨西哥城发生的小儿腹泻的可能病原体——肠道致病菌进行了调查。62例病例中有47例(76%)鉴定出了病原体。16例检测到轮状病毒颗粒。29例检测到产肠毒素大肠杆菌;11例不耐热肠毒素呈阳性,18例仅耐热肠毒素呈阳性。15例(24%)研究对象同时发现多种病原体。这项研究表明,墨西哥城小儿夏季腹泻的病因多种多样。产肠毒素大肠杆菌和轮状病毒是最常遇到的病原体,但它们经常与其他病原体一起出现。仅产耐热肠毒素的大肠杆菌菌株与产不耐热肠毒素大肠杆菌的检出频率相同,这表明在未来的现场研究中必须同时寻找这两种产肠毒素大肠杆菌。

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