Ornellas Antonio Augusto, Frota Rodrigo, Lopes da Silva Luis Felipe, Dauster Breno, Quirino Raul, de Santos Schwindt Aline Barros, Pereira Maria Rita
Department of Urology, Instituto Nacional de Câncer, Rio de Janeiro, Brazil. Luis Felipe Lopes da Silva
Urol Int. 2009;82(4):477-80. doi: 10.1159/000218541. Epub 2009 Jun 8.
Sebaceous carcinoma is a very aggressive malignant tumor, derived from the adnexal epithelium of sebaceous glands. Extraocular sebaceous carcinoma is a very uncommon neoplasm usually localized on the head and neck. To our knowledge, there are only 2 previously reported cases of sebaceous carcinoma on the penis. We report the clinicopathologic data on 3 additional cases of sebaceous carcinoma arising in the penis. Treatment is debatable in view of the fact that this kind of tumor has a high recurrence rate and early regional lymph node involvement. Considering these facts, we used preoperative lymphoscintigraphy, intraoperative lymph node mapping and sentinel node biopsy before performing a bilateral inguinal lymphadenectomy in 1 of 3 patients treated in our institute.