Witt Robert L, Rejto Lidia
Head and Neck Multidisciplinary Clinic, Helen F. Graham Cancer Center, USA.
Del Med J. 2009 Mar;81(3):119-25.
To determine if Extracapsular Dissection (ECD) versus Partial Superficial Parotidectomy (PSP) differ in terms of tumor recurrence and transient and permanent facial nerve dysfunction. ECD does not dissect the facial nerve. PSP dissects the facial nerve and provides a 1-2 cm margin around the tumor.
A 38-year Ovid Medline search (1970-2008) and an historical review with statistical analysis of published manuscripts were performed.
Tumor recurrence occurred in 36/1183 (3.0%) ECD cases and 1/340 (0.3%) PSP cases; (p < 0.05). Permanent facial nerve dysfunction occurred in 22/1202 (1.8%) ECD cases and 2/924 (0.2%) PSP cases; (p < 0.05). Transient facial nerve dysfunction occurred in 112/1036 (11.8%) ECD cases and 142/793 (17.9%) PSP cases; (p < 0.05%).
Historical review with statistical analysis of published series demonstrate a significantly higher rate of recurrent pleomorphic adenoma and permanent facial nerve dysfunction and a lower rate of transient facial nerve dysfunction with ECD compared to PSP.
确定囊外剥离术（ECD）与部分浅叶腮腺切除术（PSP）在肿瘤复发、暂时性和永久性面神经功能障碍方面是否存在差异。ECD不解剖面神经。PSP解剖面神经并在肿瘤周围提供1-2厘米的切缘。
进行了一项为期38年的Ovid Medline检索（1970-2008年），并对已发表手稿进行了历史回顾和统计分析。
1183例ECD病例中有36例（3.0%）发生肿瘤复发，340例PSP病例中有1例（0.3%）发生肿瘤复发；（p<0.05）。1202例ECD病例中有22例（1.8%）出现永久性面神经功能障碍，924例PSP病例中有2例（0.2%）出现永久性面神经功能障碍；（p<0.05）。1036例ECD病例中有112例（11.8%）出现暂时性面神经功能障碍，793例PSP病例中有142例（17.9%）出现暂时性面神经功能障碍；（p<0.05%）。
对已发表系列进行的历史回顾和统计分析表明，与PSP相比，ECD复发性多形性腺瘤和永久性面神经功能障碍的发生率显著更高，而暂时性面神经功能障碍的发生率更低。
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