Serrao Sebastiano, Lombardo Giuseppe, Lombardo Marco, Palombi Marino, Roberts Cynthia J
Serraolaser, Rome, Italy.
J Refract Surg. 2009 May;25(5):451-8. doi: 10.3928/1081597X-20090422-08.
To analyze the 6-year response of corneal topography to photorefractive keratectomy (PRK) for myopia and myopic astigmatism.
Twenty patients (40 eyes) who had PRK using the Technolas Keracor 217C excimer laser platform were followed up to 6 years after surgery. The eyes were subdivided into three groups according to the preoperative spherical equivalent refraction and astigmatism component. Corneal topographic maps were obtained with a Placido disk topographer (Keratron Scout). The pre- and postoperative topographical data were imported into custom software, which computed the average composite corneal map and average difference map for each study group to quantify the anterior corneal changes following laser ablation. The software defined three concentric zones of the surface topography, allowing characterization of the regional corneal response following surgery.
At 6 years, no changes in the surface topographic configuration of the central cornea were assessed following spherical myopic ablations in comparison with 1 year postoperatively. A slight peripheral flattening of approximately 0.60 diopters (D) (P < .001) was measured following the higher myopic ablations at 6 years compared with 1 year postoperatively. Minimal changes, of approximately 0.30 D (P < .001), in the anterior central cornea were observed following astigmatic correction during follow-up.
Photorefractive keratectomy for the correction of myopia provides stable comeal topography, with no clinically significant changes in the curvature profile at 6 years after surgery.
分析准分子激光角膜切削术(PRK)治疗近视及近视散光后6年的角膜地形图变化情况。
对20例(40只眼)使用Technolas Keracor 217C准分子激光平台行PRK手术的患者进行术后6年随访。根据术前等效球镜度和散光成分将患眼分为三组。使用Placido盘角膜地形图仪(Keratron Scout)获取角膜地形图。将术前和术后的地形图数据导入定制软件,该软件计算每个研究组的平均复合角膜地形图和平均差异地形图,以量化激光消融后角膜前部的变化。该软件定义了表面地形图的三个同心区域,以便对术后区域角膜反应进行特征描述。
6年时,与术后1年相比,近视性球镜消融术后中央角膜表面地形构型无变化。与术后1年相比,6年时高度近视性消融术后周边角膜有轻微变平,约0.60屈光度(D)(P <.001)。随访期间散光矫正后,中央角膜前部有微小变化,约0.30 D(P <.001)。
准分子激光角膜切削术矫正近视可提供稳定的角膜地形图,术后6年角膜曲率轮廓无临床显著变化。