Namikawa Y, Horiuchi T, Yamada Y
Department of Ophthalmology, Jikei University School of Medicine, Minato-ku Japan.
Nippon Ganka Gakkai Zasshi. 1991 Aug;95(8):767-70.
Experimental choroidal circulatory disorder was induced by diathermy coagulation in albino rabbit to investigate the effect of oxygen on choroidal blood flow in the area. Choroidal blood flow was measured by a hydrogen clearance method using electrolysis before and after the oxygen inhalation. Oxygen was inhaled for 30 minutes at 1 atmosphere using an open mask method in order to stabilize the arterial blood CO2 concentration. After inhalation of oxygen, normal choroidal blood flow showed a 24.9% decrease from control value, but no significant difference was seen in experimental choroidal circulatory disorder. These results suggested that the inner tissue metabolic CO2 inhibited the effect of vascular constriction in hyperoxemia.
通过对白化兔进行透热凝固诱导实验性脉络膜循环障碍，以研究氧气对该区域脉络膜血流的影响。在吸氧前后，采用电解氢清除法测量脉络膜血流。使用开放式面罩法在1个大气压下吸氧30分钟，以稳定动脉血二氧化碳浓度。吸氧后，正常脉络膜血流较对照值下降了24.9%，但在实验性脉络膜循环障碍中未观察到显著差异。这些结果表明，内部组织代谢产生的二氧化碳抑制了高氧血症时血管收缩的作用。
