Kransdorf M J, Meis J M, Jelinek J S
Department of Radiologic Pathology, Armed Forces Institute of Pathology, Washington, DC 20306-6000.
AJR Am J Roentgenol. 1991 Dec;157(6):1243-8. doi: 10.2214/ajr.157.6.1950874.
We reviewed retrospectively the MR images of eight histologically proved cases of myositis ossificans and correlated the MR appearance with the histologic findings, as well as with other radiologic studies. Patients with available MR images were chosen from a group of 326 cases in our radiologic archives of histologically proved and radiologically correlated myositis ossificans. In addition to MR images, all patients had plain radiographs, six had CT scans, and two had arteriograms. On T2-weighted spin-echo MR, the lesions were relatively well defined and inhomogeneous and had intermediate to high signal intensity. The latter corresponded to a central proliferating core of fibroblasts and myofibroblasts with a myxoid stroma resembling nodular fasciitis, rimmed by osteoblasts with bone production. Edema surrounded lesions less than a few months old. T1-weighted images of early lesions were normal or showed evidence of a mass by displacement of fat planes. Hemorrhage and fluid-fluid levels were seen in one lesion of intermediate duration. Mature lesions tended to be well defined with inhomogeneous signal intensity, similar to that of fat, representing areas of fat situated between bone trabeculae within the lesion. We present the MR appearance of myositis ossificans and correlate it with other radiologic studies and the histologic findings. The varying appearance of myositis ossificans relates to the histologic changes that occur as the disorder progresses. Knowledge of the MR appearance of myositis ossificans is important in that the lesion has many of the MR imaging characteristics frequently associated with malignancy.
我们回顾性地分析了8例经组织学证实的骨化性肌炎患者的磁共振成像（MR）图像，并将MR表现与组织学结果以及其他影像学检查结果进行了关联。有可用MR图像的患者是从我们放射学档案中的326例经组织学证实且与放射学相关的骨化性肌炎病例中挑选出来的。除了MR图像外，所有患者均有X线平片，6例有CT扫描，2例有动脉造影。在T2加权自旋回波MR上，病变相对边界清晰且不均匀，信号强度为中等至高信号。后者对应于成纤维细胞和肌成纤维细胞的中央增殖核心，伴有类似结节性筋膜炎的黏液样基质，周围有成骨细胞并伴有骨形成。水肿围绕着病程小于几个月的病变。早期病变的T1加权图像正常或通过脂肪平面移位显示有肿块迹象。在一个病程中等的病变中可见出血和液-液平面。成熟病变往往边界清晰，信号强度不均匀，类似于脂肪，代表病变内骨小梁之间的脂肪区域。我们展示了骨化性肌炎的MR表现，并将其与其他影像学检查结果和组织学发现进行了关联。骨化性肌炎的不同表现与疾病进展过程中发生的组织学变化有关。了解骨化性肌炎的MR表现很重要，因为该病变具有许多常与恶性肿瘤相关的MR成像特征。
