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[人类原发性肝癌细胞质沉积物的超微结构及酶学研究]

[Ultrastructure of cytoplasmic deposits and enzyme studies in human primary liver cancer].

作者信息

Strausz J, Lapis K

出版信息

Morphol Igazsagugyi Orv Sz. 1977 Apr;17(2):118-24.

PMID:195199
Abstract

Authors examined of the fine structure and electronhistochemical properties of deposits observed in two cases of primary liver carcinoma. It was established, that these deposits are formed by filaments consisting of fine granules of 70 A in diameter. On the basis of morphological picture and results of the investigation by enzymatic-dogestion technique it is believed, that deposits are the product of the rough-surfaced endoplasmic reticulum and their occurrence indicate the impairment of it's function. Deposits--as revealed by the enzymatic-digestion technique--consists of complex material, the protein component of which contain large quantities of basical amino acids.

摘要

作者研究了两例原发性肝癌中观察到的沉积物的精细结构和电子组织化学特性。已确定这些沉积物由直径为70埃的细颗粒组成的细丝形成。根据形态学图像和酶消化技术的研究结果,认为沉积物是糙面内质网的产物,其出现表明其功能受损。酶消化技术显示,沉积物由复杂物质组成,其蛋白质成分含有大量碱性氨基酸。

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