Steffens David C, Fisher Gwenith G, Langa Kenneth M, Potter Guy G, Plassman Brenda L
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA.
Int Psychogeriatr. 2009 Oct;21(5):879-88. doi: 10.1017/S1041610209990044. Epub 2009 Jun 12.
Previous studies have attempted to provide estimates of depression prevalence in older adults. The Aging, Demographics and Memory Study (ADAMS) is a population-representative study that included a depression assessment, providing an opportunity to estimate the prevalence of depression in late life in the U.S.A.
The ADAMS sample was drawn from the larger Health and Retirement Study. A total of 851 of 856 ADAMS participants aged 71 and older had available depression data. Depression was measured using the Composite International Diagnostic Interview - Short Form (CIDI-SF) and the informant depression section of the Neuropsychiatric Inventory (NPI). We estimated the national prevalence of depression, stratified by age, race, sex, and cognitive status. Logistic regression analyses were performed to examine the association of depression and previously reported risk factors for the condition.
When combining symptoms of major or minor depression with reported treatment for depression, we found an overall depression prevalence of 11.19%. Prevalence was similar for men (10.19%) and women (11.44%). Whites and Hispanics had nearly three times the prevalence of depression found in African-Americans. Dementia diagnosis and pain severity were associated with increased depression prevalence, while black race was associated with lower rates of depression.
The finding of similar prevalence estimates for depression in men and women was not consistent with prior research that has shown a female predominance. Given the population-representativeness of our sample, similar depression rates between the sexes in ADAMS may result from racial, ethnic and socioeconomic diversity.
以往的研究试图估算老年人中抑郁症的患病率。老龄化、人口统计学与记忆研究(ADAMS)是一项具有人口代表性的研究,其中包括抑郁症评估,为估算美国老年人中抑郁症的患病率提供了契机。
ADAMS样本取自规模更大的健康与退休研究。856名71岁及以上的ADAMS参与者中,共有851人有可用的抑郁症数据。使用综合国际诊断访谈简表(CIDI-SF)和神经精神科问卷(NPI)的 informant 抑郁症部分来测量抑郁症。我们估算了按年龄、种族、性别和认知状态分层的全国抑郁症患病率。进行逻辑回归分析以检验抑郁症与先前报道的该病症风险因素之间的关联。
将重度或轻度抑郁症的症状与报告的抑郁症治疗情况相结合时,我们发现总体抑郁症患病率为11.19%。男性(10.19%)和女性(11.44%)的患病率相似。白人和西班牙裔的抑郁症患病率几乎是非裔美国人的三倍。痴呆症诊断和疼痛严重程度与抑郁症患病率增加相关,而黑人种族与较低的抑郁症患病率相关。
男性和女性抑郁症患病率估算值相似这一发现与先前显示女性占主导地位的研究不一致。鉴于我们样本的人口代表性,ADAMS中两性之间相似的抑郁症患病率可能是由于种族、民族和社会经济多样性所致。