Grunebaum Michael F, Oquendo Maria A, Manly Jennifer J
Department of Psychiatry, the College of Physicians and Surgeons, Columbia University, United States.
J Affect Disord. 2008 Jan;105(1-3):273-7. doi: 10.1016/j.jad.2007.04.022. Epub 2007 May 25.
There are limited data on depressive symptoms and antidepressant use in ethnically diverse, urban elderly.
Analysis of depressive symptom and antidepressant use data from an epidemiological survey of dementia in an ethnically diverse, urban, elderly community.
21.5% (N=566) reported clinically significant depressive symptoms. Severity was inversely associated with socioeconomic status. 7.5% (N=194) reported antidepressant medication use. Multiple logistic regression analysis adjusting for severity and other covariates showed that men and African Americans had nearly half the odds of using antidepressants. Antidepressant use was more frequent among Hispanics, those with more severe depression and more medical illness.
Combined sample; CES-D not validated in Hispanics and inner-city African Americans; depressive symptoms assessed at one time-point; lack of complete income data; geographically restricted.
In this elder sample, taking into account depressive symptom severity and other confounds, antidepressant use is nearly half as likely among men and African Americans.
关于种族多样化的城市老年人抑郁症状及抗抑郁药物使用情况的数据有限。
对一个种族多样化的城市老年社区进行的痴呆症流行病学调查中的抑郁症状及抗抑郁药物使用数据进行分析。
21.5%(N = 566)报告有临床显著的抑郁症状。严重程度与社会经济地位呈负相关。7.5%(N = 194)报告使用抗抑郁药物。在对严重程度和其他协变量进行调整的多因素逻辑回归分析中,男性和非裔美国人使用抗抑郁药物的几率几乎减半。西班牙裔、抑郁症更严重以及患有更多疾病的人群中抗抑郁药物使用更为频繁。
混合样本;CES - D量表在西班牙裔和市中心非裔美国人中未经验证;抑郁症状在一个时间点进行评估;缺乏完整的收入数据;地域受限。
在这个老年样本中,考虑到抑郁症状严重程度和其他混杂因素,男性和非裔美国人使用抗抑郁药物的可能性几乎减半。