Li Shiming, Xiong Ying, Li Jing, Wang Ningli, Dai Yun, Xue Lixia, Zhao Haoxin, Jiang Wenhan, Zhang Yudong, He Ji C
Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Optom Vis Sci. 2009 Jul;86(7):868-74. doi: 10.1097/OPX.0b013e3181adfdff.
To investigate the effect on visual acuity of correcting specific Zernike aberrations.
Visual acuity was tested for 12 young subjects using a Freiburg Acuity Test procedure under conditions with wavefront aberrations corrected by an adaptive optics system. The adaptive optics system consists of a Hartmann-Shack wavefront sensor, a deformable mirror, relevant optical channels and closed loop control system. Five aberration correction paradigms were used to correct different Zernike terms.
With the second order aberration fully corrected, a significant improvement in visual acuity was observed (0.056 logMAR, t = 2.79, p = 0.018). Further correction of third order Zernike aberrations resulted in an additional improvement of 0.041 logMAR (t = 2.63, p = 0.023). But an additional correction of spherical aberration did not produce a significant increase in visual acuity (t = 1.10, NS). Full correction of aberrations achieved the best visual acuity with an improvement of 0.022 logMAR (t = 2.46, p = 0.032). The visual acuity was found to increase with the root mean square values of the residual aberrations with a linear relationship (r = 0.63, p < 0.0001).
Correction of monochromatic wavefront aberrations improves visual acuity for normal eyes and the improvement of visual acuity is proportional to the change of root mean square of wavefront aberrations.
研究矫正特定泽尼克像差对视敏度的影响。
使用弗莱堡视敏度测试程序,在自适应光学系统校正波前像差的条件下,对12名年轻受试者的视敏度进行测试。自适应光学系统由哈特曼-夏克波前传感器、可变形镜、相关光学通道和闭环控制系统组成。使用五种像差校正范式来校正不同的泽尼克项。
在二阶像差完全校正后,观察到视敏度有显著提高(0.056 logMAR,t = 2.79,p = 0.018)。进一步校正三阶泽尼克像差导致视敏度额外提高0.041 logMAR(t = 2.63,p = 0.023)。但额外校正球差并未使视敏度显著增加(t = 1.10,无显著性差异)。像差的完全校正实现了最佳视敏度,提高了0.022 logMAR(t = 2.46,p = 0.032)。发现视敏度随残余像差的均方根值增加呈线性关系(r = 0.63,p < 0.0001)。
单色波前像差的校正可提高正常眼睛的视敏度,视敏度的提高与波前像差均方根的变化成正比。