用于通过重氮化合物和酰氯构建环戊烯酮的多步一锅法维蒂希/纳扎罗夫反应。

Multistep one-pot Wittig/Nazarov reaction for construction of cyclopentenone with diazo compounds and acid chlorides.

作者信息

Cao Peng, Sun Xiu-Li, Zhu Ben-Hu, Shen Qi, Xie Zuowei, Tang Yong

机构信息

State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China.

出版信息

Org Lett. 2009 Jul 16;11(14):3048-51. doi: 10.1021/ol901086f.

DOI:10.1021/ol901086f

PMID:19522525

Abstract

A facile multistep one-pot synthesis of single or fused cyclopentenones has been developed. The sequence involves a transition metal-catalyzed ylide formation/Wittig Olefination/Nazarov Cyclization.

摘要

已经开发出一种简便的多步一锅法合成单环或稠合环戊烯酮的方法。该序列包括过渡金属催化的叶立德形成/维蒂希烯烃化/纳扎罗夫环化反应。