Laggari Varvara, Diareme Stavroula, Christogiorgos Stylianos, Deligeoroglou Efthimios, Christopoulos Panagiotis, Tsiantis John, Creatsas George
Department of Child Psychiatry, University of Athens Medical School, Aghia Sophia Children's Hospital, Athens, Greece.
J Psychosom Obstet Gynaecol. 2009 Jun;30(2):83-8. doi: 10.1080/01674820802546204.
The purpose of this study was to assess self-reported depressive and anxiety symptoms in adolescents with polycystic ovary syndrome (PCOS) and those with the rare Mayer-Rokitansky-Kuster-Hauser Syndrome (MRKHS), compared with healthy adolescents.
The participants were 49 adolescent girls, of whom 27 were patients with confirmed menstrual disorder, 22 with PCOS and 5 with MRKHS; and 22 were healthy eumenorrheic adolescents (control group) matched by age and school grade. The Beck Depression Inventory (BDI) and the State-Trait Anxiety Inventory (STAI-Gr) were used to measure depression and anxiety, respectively.
The results showed that it was 1.08 times more likely for the PCOS group (p = 0.043) and 1.12 times more likely for the MRKHS group (p = 0.039) to have higher scores than healthy adolescents on the anxiety scale. The MRKHS group was 1.40 times more likely to have a higher number of depressive symptoms (p = 0.040) than the control group.
These findings, although based on a small sample, suggest a relationship between PCOS and MRKHS and the presence of psychological problems, such as anxiety and depressive symptoms in adolescents. This study is among the first to examine psychological difficulties in adolescents with such a rare menstrual syndrome as MRKHS.
本研究旨在评估多囊卵巢综合征（PCOS）青少年患者以及罕见的迈耶-罗基坦斯基-库斯特-豪泽综合征（MRKHS）患者自我报告的抑郁和焦虑症状，并与健康青少年进行比较。
研究对象为49名青春期女孩，其中27名患有确诊的月经紊乱，22名患有PCOS，5名患有MRKHS；22名健康的月经正常青少年（对照组），根据年龄和年级进行匹配。分别使用贝克抑郁量表（BDI）和状态-特质焦虑量表（STAI-Gr）来测量抑郁和焦虑。
结果显示，PCOS组在焦虑量表上得分高于健康青少年的可能性是其1.08倍（p = 0.043），MRKHS组在焦虑量表上得分高于健康青少年的可能性是其1.12倍（p = 0.039）。MRKHS组出现抑郁症状数量高于对照组的可能性是其1.40倍（p = 0.040）。
尽管本研究基于小样本，但这些发现表明PCOS和MRKHS与青少年心理问题（如焦虑和抑郁症状）之间存在关联。本研究是首批研究患有MRKHS这种罕见月经综合征青少年心理困难的研究之一。
